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Record W3175693290 · doi:10.1096/fasebj.20.4.a599-a

INDUCED FIBER VISCOSITY TRIPLES ITS EFFECT ON POSTPRANDIAL BLOOD GLUCOSE RESPONSE

2006· article· en· W3175693290 on OpenAlexaffabout
Pearl L Breitman, Adish Ezatagha, Shirin Panahi, Vladimir Vuksan

Bibliographic record

VenueThe FASEB Journal · 2006
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMetabolism, Diabetes, and Cancer
Canadian institutionsMuscular Dystrophy CanadaUniversity of Toronto
Fundersnot available
KeywordsPostprandialViscosityBlood viscosityFiberInternal medicineFood scienceChemistryMedicineMaterials scienceInsulinComposite material

Abstract

fetched live from OpenAlex

This study examined the effects of modifying fiber viscosity, by dose and treatment methods, on glycemic response. On 16 occasions, in a single‐blinded, randomized, crossover design, 8 healthy subjects (4M:4F, 33.6±3.5 yrs) consumed glucose drinks (with 25 or 50g carbohydrates (CHO)) plus psyllium (0,3,6or 9g) that was either treated (induced viscosity) or untreated (inherent viscosity). The induced viscosity treatment was a combination of heat, mechanical energy, aeration and gradual cooling. Hardness, which is highly correlated with viscosity (r=0.98, p=0.0034), was used to measure meal viscosity (Instron, Canton, MA). Log hardness was directly proportional to dose (r=0.99, p=0.0056) and heat treatment (r=0.99, p<0.0002) and inversely proportional (p=0.002) to incremental blood glucose area under the curve (AUC) at 25g (r=−1.00, p=0.0001) and 50g (r=−0.094, p=0.0004) CHO. A strong inverse correlation existed between fiber‐to‐nutrient ratio and % AUC reduction (inherent: r=−0.95, p=0.0043; induced: r=−0.098, p=0.0009). Viscosity of meals is an important predictor of postprandial glycemic response when fiber‐to‐nutrient ratio is considered. A novel procedure that treats soluble fiber to triple its viscosity and reduce postprandial blood glucose can be highly regarded by industry, since it may be easier to incorporate into foods, and also by individuals, who could consume fiber at lower quantities and still achieve health benefits. Travel grant: Inovobiologic Inc. Calgary

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.241
Teacher spread0.232 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2006
Admission routes2
Has abstractyes

Explore more

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