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Record W3175981121 · doi:10.1096/fasebj.20.4.a596-c

Effect of a vegan based high protein, low carbohydrate diet on weight loss and serum lipids

2006· article· en· W3175981121 on OpenAlexaff
Julia MW Wong, Amin Esfahani, Cyril W.C. Kendall, David J.A. Jenkins

Bibliographic record

VenueThe FASEB Journal · 2006
Typearticle
Languageen
FieldMedicine
TopicDiet and metabolism studies
Canadian institutionsUniversity of TorontoSt. Michael's Hospital
Fundersnot available
KeywordsWeight lossBioelectrical impedance analysisCarbohydrateBlood lipidsFood scienceOverweightSoy proteinVegan DietObesitySaturated fatMedicineChemistryCholesterolInternal medicineBody mass index

Abstract

fetched live from OpenAlex

Background High protein, low carbohydrate diets, such as the Atkins’ diet, have gained popularity in recent years as weight loss strategies. However, high amounts of animal protein and its associated saturated fat, in the absence of weight loss, may result in undesirable effects on the lipid profile and increase coronary heart disease risk. Objective To determine if exchange of saturated fat and animal protein for monounsaturated fat and vegetable protein, mainly from soy, will result in a significant effect on blood lipids while still encouraging weight loss. Method Thirty overweight hyperlipidemic subjects will each undergo 1 of 2 interventions for 1 month: a diet high in vegetable proteins and vegetable fats (26% carbohydrate, 30% protein, 44% fat) or a diet very low in saturated fat, based on milled whole‐wheat cereals and low‐fat dairy foods (58% carbohydrate, 16% protein, 26% fat). Subjects will consume 70% of their estimated energy requirements and all study foods will be provided. Fasting blood lipids and glucose, blood pressure and body weight will be measured at weeks 0, 2 and 4, with body composition (Bioelectrical Impedance Analysis) measured at baseline and at the end of the treatment. Results Twenty‐five hyperlipidemic subjects have been recruited thus far. Preliminary data will be presented. Conclusion A diet where carbohydrates are exchanged for unsaturated fats, such as vegetable oils and nuts, and high animal protein for vegetable proteins, such as soy, may result in significant weight loss and significant improvements in metabolic risk factors for CHD. Research support: Solae Company

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Non-randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.222
Teacher spread0.217 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNon-randomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2006
Admission routes1
Has abstractyes

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