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Post‐Metabolic Response to Exercise in Normobaric Hypoxia

2013· article· en· W3176193331 on OpenAlexaff
Liam Kelly, Fabien A. Basset

Bibliographic record

VenueThe FASEB Journal · 2013
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicHigh Altitude and Hypoxia
Canadian institutionsMemorial University of Newfoundland
Fundersnot available
KeywordsHypoxia (environmental)MedicineInternal medicineBasal metabolic rateEndocrinologyAnimal scienceChemistryBiologyOxygen

Abstract

fetched live from OpenAlex

The purpose of the study was to examine post‐metabolic response to constant workload exercise (CWE) under normobaric hypoxia. Seven active healthy males (age: 26±4 yrs; height: 176±4 cm; weight: 78±10 kg; BMI: 25±3 kg•m −2 ; VO 2max : 4.0±0.3 L•min −1 ) randomly underwent normoxic and hypoxic (F i O 2 = 0.15) CWE. Each experimental session consisted of a basal metabolic rate determination (BMR), 60‐min of CWE, and 60‐min of post‐exercise metabolic rate measurement. For each condition, 24‐hr post‐treatment BMR was recorded. Absolute workload was determined during a graded cycling test in normoxia and set at 50% of participants’ peak power (314±26 W) for both conditions. There was a significant condition/time (0–20; 21–40, and 41–60‐min) interaction on post‐exercise lipid metabolism ( p = 0.015). Fat contribution was 47±19%, 60±9% and 51±12% in normoxia; and 79±20%, 79±19% and 62±24% in hypoxia, for each epoch, respectively. Although not statistically significant, fat contribution 24‐hrs after the hypoxic intervention was elevated 3% above baseline. In conclusion, exercise in hypoxia contributed to an increase reliance on fat oxidation post‐treatment up to 24‐hrs. This result was explained by higher glycolytic flux during exercise under hypoxia compared to normoxia at the same absolute workload.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.232
Teacher spread0.224 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2013
Admission routes1
Has abstractyes

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