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Dietary fat and carbohydrate intake during early pregnancy and risk of gestational diabetes

2011· article· en· W3176252298 on OpenAlexaff
Sylvia H. Ley, Anthony J Hanley, Ravi Retnakaran, Mathew Sermer, Bernard Zinman, Deborah L. O’Connor

Bibliographic record

VenueThe FASEB Journal · 2011
Typearticle
Languageen
FieldMedicine
TopicGestational Diabetes Research and Management
Canadian institutionsHospital for Sick ChildrenMount Sinai HospitalUniversity of Toronto
Fundersnot available
KeywordsGestational diabetesMedicinePregnancyObstetricsOdds ratioGestationDiabetes mellitusPhysiologyInternal medicineEndocrinologyBiology

Abstract

fetched live from OpenAlex

Dietary intake is known to influence gestational diabetes (GDM), but there is a little consensus on the optimal distribution of dietary fat and carbohydrate intake during pregnancy for GDM prevention. We aimed to investigate the impact of macronutrient intake distribution during the second trimester on the risk of GDM. Women who were with singleton pregnancies and without pre‐existing diabetes were included. Participants were asked to recall second trimester dietary intake using a validated food frequency questionnaire and in addition underwent a 3‐hour oral glucose tolerance test. Of 205 participants, 46 (22.4%) had GDM assessed at 30±2.6 (mean±SD) weeks gestation. Women who had GDM compared to those free of GDM consumed higher % intake of total fat (mean±SD: 37±5.2 v. 34±5.3 %, respectively) and lower % intake of carbohydrate (49±6.2 v. 52±6.2 %) (both p=0.01). After adjustment for age, ethnicity, family history of diabetes, prepregnancy BMI, and pregnancy weight gain, % total fat and % carbohydrate intake were individually associated with GDM (odds ratio per 5% increase 1.54 [95% CI 1.04–2.29] and 0.68 [0.49–0.93], respectively). In conclusion, dietary intakes higher in total fat and lower in carbohydrate, potential modifiable behavioral determinants, during early pregnancy were associated with increased risk for GDM later in pregnancy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.008
Threshold uncertainty score0.016

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.242
Teacher spread0.217 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2011
Admission routes1
Has abstractyes

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