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Application of biosensors based on nanomaterials in cancer cell detection

2021· article· en· W3177060570 on OpenAlexaff
Yizhou Zhang, Hongling Lyu

Bibliographic record

VenueJournal of Physics Conference Series · 2021
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicAdvanced biosensing and bioanalysis techniques
Canadian institutionsUniversity of Waterloo
Fundersnot available
KeywordsBiosensorCancer detectionNanotechnologyCancerCancer cellNanomaterialsMaterials scienceMedicineInternal medicine

Abstract

fetched live from OpenAlex

Abstract Cancer, killing millions of people every year, is the most serious disease in the world. The survival of cancer patients is closely related to the diagnosis of cancer cells. Therefore, in the early stage of cancer, the detection of cancer biomarkers from cellular level is of great significance to improve the survival rate of cancer patients. Nanomaterials-based biosensors play the increasingly important role in the treatment of cancer, owing to their ultra-high sensitivity and high selectivity. Nowadays, it is widely used in the detection of cancer cells to provide reference for cancer treatment. Herein, the present minireview summarizes application of nanomaterials-based biosensors for the detection of cancer cells, such as colorimetric biosensors, fluorescence biosensors, surface-enhanced Raman scattering (SERS) biosensors, electrochemical biosensors and other types of biosensors. We further introduce the construction principle of these biosensing methods, and compare the advantages of these biosensors in detecting cancer cells.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.023
Threshold uncertainty score0.272

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.270
Teacher spread0.258 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations15
Published2021
Admission routes1
Has abstractyes

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