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Record W3179197834 · doi:10.1002/jac5.1501

A practical introduction to conducting and using <scp>case‐control</scp> studies

2021· article· en· W3179197834 on OpenAlexaff
Cynthia A. Jackevicius

Bibliographic record

VenueJACCP JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY · 2021
Typearticle
Languageen
FieldMathematics
TopicStatistical Methods in Clinical Trials
Canadian institutionsInstitute for Clinical Evaluative SciencesUniversity of TorontoUniversity Health Network
Fundersnot available
KeywordsContext (archaeology)Observational studyControl (management)OddsSelection (genetic algorithm)Key (lock)Selection biasComputer scienceMedicineManagement scienceRisk analysis (engineering)EngineeringArtificial intelligencePathologyComputer securityInternal medicine

Abstract

fetched live from OpenAlex

Abstract Case‐control studies are a commonly encountered observational study design in pharmacy practice and pharmacotherapy research. This practical introduction to conducting and using case‐control studies focuses on the key risk of bias concepts related to the selection of cases and controls and measurement of the exposure. This article also explains how to calculate and interpret odds ratios for exposure in the context of case‐control studies. Finally, considerations for the applicability of case‐control study findings are provided in the context of clinical decision‐making around harmful exposures. Practical checklists are provided for users and researchers conducting case‐control studies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.114
metaresearch head score (Gemma)0.248
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.886
Threshold uncertainty score0.602

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1140.248
Meta-epidemiology (narrow)0.0030.003
Meta-epidemiology (broad)0.0030.003
Bibliometrics0.0070.005
Science and technology studies0.0020.005
Scholarly communication0.0040.006
Open science0.0050.005
Research integrity0.0060.012
Insufficient payload (model declined to judge)0.0610.036

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.740
GPT teacher head0.664
Teacher spread0.076 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
DomainMethods
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2021
Admission routes1
Has abstractyes

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Same venueJACCP JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACYSame topicStatistical Methods in Clinical TrialsFrench-language works237,207