MétaCan
Menu
Back to cohort
Record W3180383583 · doi:10.1002/pol.20210366

<scp>Self‐assembled free‐floating</scp> nanomaterials from <scp>sequence‐defined</scp> polymers

2021· article· en· W3180383583 on OpenAlexafffund
Jon Babi, Linglan Zhu, Angela Lin, Azalea Uva, Hana El‐Haddad, Atang Peloewetse, Helen Tran

Bibliographic record

VenueJournal of Polymer Science · 2021
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicAdvanced biosensing and bioanalysis techniques
Canadian institutionsUniversity of Toronto
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsNanotechnologySequence (biology)Self-assemblyPolymerDNA nanotechnologyNanomaterialsNanostructureComputer scienceMaterials scienceDNAChemistry

Abstract

fetched live from OpenAlex

Abstract Sequence‐defined polymers can be programmed to self‐assemble into precise nanostructures for applications in biosensing, drug delivery, optics, and molecular computation. Inspired by the natural self‐assembly processes present in biological protein and DNA systems, sets of molecular design rules have emerged across materials classes as instructions to build a variety of tunable structures. This review highlights recent advances in self‐assembled sequence‐defined and sequence‐specific polymers across peptides, peptoids, DNA, and non‐biological synthetic materials, with a focus on synthesis, assembly processes and overall structure. Specifically, these self‐assembled structures are free‐floating, as such constructs can potentially serve as a platform for the aforementioned applications. Emphasis is placed on the molecular design of polymers that self‐assemble into zero‐dimensional, one‐dimensional, two‐dimensional, or three‐dimensional nanostructures. With the development of automated syntheses and increasing control over self‐assembly, future work may focus on emerging classes of compatible hybrid materials with exciting directions toward new architectures and applications.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.274
Teacher spread0.261 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations11
Published2021
Admission routes2
Has abstractyes

Explore more

Same venueJournal of Polymer ScienceSame topicAdvanced biosensing and bioanalysis techniquesFrench-language works237,207