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Record W3184111456 · doi:10.3389/fcomp.2021.592296

Spine and Individual Vertebrae Segmentation in Computed Tomography Images Using Geometric Flows and Shape Priors

2021· article· en· W3184111456 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueFrontiers in Computer Science · 2021
Typearticle
Languageen
FieldEngineering
TopicMedical Imaging and Analysis
Canadian institutionsMcGill UniversityMontreal Neurological Institute and Hospital
FundersNatural Sciences and Engineering Research Council of CanadaFonds de recherche du Québec – Nature et technologiesCanadian Institutes of Health Research
KeywordsSegmentationComputer scienceArtificial intelligenceContext (archaeology)Pipeline (software)Prior probabilityComputer visionSurgical planningVertebral columnRadiologyMedicineAnatomyGeologyBayesian probability

Abstract

fetched live from OpenAlex

The surgical treatment of injuries to the spine often requires the placement of pedicle screws. To prevent damage to nearby blood vessels and nerves, the individual vertebrae and their surrounding tissue must be precisely localized. To aid surgical planning in this context we present a clinically applicable geometric flow based method to segment the human spinal column from computed tomography (CT) scans. We first apply anisotropic diffusion and flux computation to mitigate the effects of region inhomogeneities and partial volume effects at vertebral boundaries in such data. The first pipeline of our segmentation approach uses a region-based geometric flow, requires only a single manually identified seed point to initiate, and runs efficiently on a multi-core central processing unit (CPU). A shape-prior formulation is employed in a separate second pipeline to segment individual vertebrae, using both region and boundary based terms to augment the initial segmentation. We validate our method on four different clinical databases, each of which has a distinct intensity distribution. Our approach obviates the need for manual segmentation, significantly reduces inter- and intra-observer differences, runs in times compatible with use in a clinical workflow, achieves Dice scores that are comparable to the state of the art, and yields precise vertebral surfaces that are well within the acceptable 2 mm mark for surgical interventions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.809
Threshold uncertainty score0.399

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.003
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.225
Teacher spread0.214 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it