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Record W3184824189 · doi:10.21423/aabppro20143692

randomized controlled clinical trial to evaluate the effect of an intranasal respiratory vaccine on calf health, ultrasonographic lung consolidation, and growth in Holstein dairy calves

2014· article· en· W3184824189 on OpenAlexaff
T. L. Ollivett, K.E. Leslie, T.F. Duffield, D.V. Nydam, Joanne Hewson, Jeff Caswell, D.F. Kelton

Bibliographic record

VenueAmerican Association of Bovine Practitioners Conference Proceedings · 2014
Typearticle
Languageen
FieldVeterinary
TopicAnimal health and immunology
Canadian institutionsUniversity of Guelph
Fundersnot available
KeywordsMedicineBovine respiratory diseaseNasal administrationLungRandomized controlled trialRespiratory systemClinical trialInternal medicineImmunology

Abstract

fetched live from OpenAlex

Although passive transfer of antibodies to the newborn calf provides many great benefits, high levels of maternal antibodies may limit the ability of the calf to respond to parenterally administered vaccines against the respiratory viruses associated with bovine respiratory disease (BRD). Experimental challenge studies have demonstrated varying levels of efficacy of vaccines administered via the intranasal route. Unfortunately, direct identification of lung lesions associated with BRD requires euthanasia and often limits the size of study populations. As an alternative, thoracic ultrasonography (US) can be performed quickly and provides an accurate antemortem assessment of lung health. Therefore, the purpose of this randomized controlled clinical trial was to evaluate the effect of an intranasal vaccine on calf health, ultrasonographic lung lesions, and growth in young Holstein calves.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.014
metaresearch head score (Gemma)0.019
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.121
Threshold uncertainty score0.990

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0140.019
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.388
Teacher spread0.354 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2014
Admission routes1
Has abstractyes

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