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Record W3187629200 · doi:10.1503/cmaj.202258

Use of fluorescence to visualize response to iloprost treatment for frostbite

2021· article· en· W3187629200 on OpenAlexaffvenueabout
Mira MacLennan, Alexander Poole, Josianne Gauthier

Bibliographic record

VenueCanadian Medical Association Journal · 2021
Typearticle
Languageen
FieldMedicine
TopicBurn Injury Management and Outcomes
Canadian institutionsMcMaster UniversityMcMaster University Medical CentreRoyal University HospitalUniversity of SaskatchewanUniversity of Calgary
Fundersnot available
KeywordsFrostbiteIloprostMedicineSurgeryDermatologyInternal medicine

Abstract

fetched live from OpenAlex

A 48-year old man presented to the emergency department in Whitehorse, Yukon, after 8 hours of exposure to -47C. He was a nonsmoker and otherwise healthy. He had grade 2 frostbite to the left first toe, with cyanosis to the distal interphalangeal joint (Appendix 1, available at www.cmaj.ca/lookup/doi/10.1503/ cmaj.202258/tab-related-content). We used intravenous indocyanine green fluorescence, a water-soluble dye, for baseline visual microvascular assessment and to assess treatment response. We started iloprost 0.2 g/mL at 10 mL/h and increased it to 50 mL/h for 6 hours daily for 5 days. We captured fluorescence images before iloprost treatment (Figure He tolerated treatment well and did not require amputation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.009
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.246
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.009
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.322
Teacher spread0.289 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2021
Admission routes3
Has abstractyes

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