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Record W3189557035 · doi:10.33844/cjm.2021.60508

Risk Factors and Therapeutic Interventions for Osteoporosis

2021· article· en· W3189557035 on OpenAlexaffvenue
Alyssa Wu, John L. Johnson, Zachary Schauer, A. A. Mardon, Terrence Wu

Bibliographic record

VenueCanadian Journal of Medicine · 2021
Typearticle
Languageen
FieldMedicine
TopicBone health and osteoporosis research
Canadian institutionsUniversity of AlbertaWestern UniversityMacEwan UniversityMcMaster University
Fundersnot available
KeywordsOsteoporosisMedicineBone mineralVitamin D and neurologyDiseasePsychological interventionPeak bone massPhysical therapyIntensive care medicineInternal medicinePediatrics

Abstract

fetched live from OpenAlex

Osteoporosis is a disease of the bone characterized by a loss in bone mineral density. Although this disease is commonly diagnosed in adults, it is not directly associated with increasing age. There are many links and potential risk factors to developing osteoporosis, including hormonal imbalances, nutrient deficiency, cardiovascular health, and exercise. This review examines how osteoporotic fractures are diagnosed using bone imaging techniques, including dual-energy X-ray absorptiometry scans. The quality of life for patients with osteoporosis is discussed concerning the protective and risk factors associated with osteoporosis. Specifically, the risk factors for osteoporosis include genetic inheritance patterns, BMI, age, and lifestyle choices (including alcohol consumption, smoking, and physical exercise). There are many protective factors for preventing osteoporotic fractures, including natural bone supplements and prebiotics. These supplements can be found in most dairy products, which are fortified with vitamin D, which can be consumed in the diet to support bone health. Prebiotics can also be used to increase the healthy proliferation of commensal gut bacteria that are used to improve the bone-building process, relieving bone breakdown during the stages of bone turnover. These therapeutic interventions can be applied to support existing patient care to prevent and maintain overall bone health.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.157
Threshold uncertainty score0.927

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.075
GPT teacher head0.371
Teacher spread0.296 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2021
Admission routes2
Has abstractyes

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