Characterization of FRI carbapenemase-producing <i>Enterobacter</i> spp. isolated from a hospital and the environment in Osaka, Japan
Bibliographic record
Abstract
The spread of antimicrobial-resistant bacteria is a global public health problem. Carbapenem-resistant Enterobacterales are major healthcare-associated pathogens that often cause outbreaks in hospitals.1 Genes encoding major carbapenemases, including IMP, VIM, NDM, KPC and OXA-48, have been increasingly detected, not only in clinical settings but also in the environment.2 French imipenemases (FRIs) are a recently discovered type of carbapenemase. FRI-1–3 were reported in Europe between 2015 and 2017.3–5 FRI-4–7 were reported in Japan and Canada between 2017 and 2019.6,7 The increasing number of reports about FRI variants suggest that FRI carbapenemases may be spreading across the world. Enterobacter asburiae 17Nkhm-UP2 and Enterobacter sp. 18A13 were isolated from a river into which effluent is discharged from a sewage treatment plant and E. asburiae 1808-013 was isolated from the urine of a patient. Drug susceptibility testing was performed using a broth microdilution method and MICs were interpreted...
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.002 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".