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Record W3191112015 · doi:10.1016/j.celrep.2021.109405

Astrocytes regulate ultra-slow arteriole oscillations via stretch-mediated TRPV4-COX-1 feedback

2021· article· en· W3191112015 on OpenAlexafffund
Jordan N. Haidey, Govind Peringod, Ádám Institóris, Kelsea A. Gorzo, Wilten Nicola, Milène Vandal, Ken‐ichi Ito, Shiying Liu, Cameron Fielding, Frank Visser, Minh Dang Nguyen, Grant R. Gordon

Bibliographic record

VenueCell Reports · 2021
Typearticle
Languageen
FieldMedicine
TopicNitric Oxide and Endothelin Effects
Canadian institutionsUniversity of Calgary
FundersCanadian Institutes of Health ResearchCumming School of Medicine, University of CalgaryHotchkiss Brain InstituteAlberta Innovates - Health SolutionsHoward Hughes Medical InstituteCanada Research ChairsUniversity of California, Los Angeles
KeywordsTRPV4ArterioleCell biologyChemistryNeuroscienceAstrocyteBiophysicsIon channelBiologyInternal medicineMedicineReceptorCentral nervous systemMicrocirculationBiochemistry

Abstract

fetched live from OpenAlex

in vivo reduces the power of vasomotion. These data demonstrate bidirectional communication between arterioles and astrocyte endfeet to regulate oscillatory microvasculature activity.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.048
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.226
Teacher spread0.217 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations69
Published2021
Admission routes2
Has abstractyes

Explore more

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