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Record W3192059233 · doi:10.1186/s12888-021-03363-3

Perceived helpfulness of treatment for generalized anxiety disorder: a World Mental Health Surveys report

2021· article· en· W3192059233 on OpenAlexaff
Dan J. Stein, Alan E. Kazdin, Ayelet Meron Ruscio, Wai Tat Chiu, Nancy A. Sampson, Hannah N. Ziobrowski, Sergio Aguilar‐Gaxiola, Jordi Alonso, Yasmin Altwaijri, Ronny Bruffaerts, Brendan Bunting, Giovanni de Girolamo, Peter de Jonge, Louisa Degenhardt, Oye Gureje, Josep María Haro, Aimée Karam, Elie G. Karam, Viviane Kovess–Masféty, Sing Lee, María Elena Medina‐Mora, Jacek Moskalewicz, Fernando Navarro‐Mateu, Daisuke Nishi, José Posada‐Villa, Kate M. Scott, María Carmen Viana, Daniel Vigo, Miguel Xavier, Zahari Zarkov, Ronald C. Kessler, Mohammed Salih Al-Kaisy, Laura Helena Andrade, Lukoye Atwoli, Corina Benjet, Guilherme Borges, Evelyn J. Bromet, José Miguel Caldas‐de‐Almeida, Graça Cardoso, Somnath Chatterji, Koen Demyttenaere, Silvia Florescu, Hristo Hinkov, Chiyi Hu, Norito Kawakami, Andrzej Kiejna, Jean‐Pierre Lépine, John J. McGrath, Zeina Mneimneh, Marina Piazza, Tim Slade, Juan Carlos Stagnaro, Margreet ten Have, Yolanda Torres, Harvey Whiteford, David R. Williams, Bogdan Wojtyniak

Bibliographic record

VenueBMC Psychiatry · 2021
Typearticle
Languageen
FieldPsychology
TopicAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Canadian institutionsUniversity of British Columbia
FundersInstituto de Salud Carlos IIIExecutive Agency for Health and ConsumersMinisterio de SaludH. Lundbeck A/SRegione PiemonteServierMinisterio de Ciencia y TecnologíaMinistry of Health, Labour and WelfareGeneralitat de CatalunyaGlaxoSmithKlinePublic Health AgencyUniversidad CESNational Insurance Institute of IsraelPan American Health OrganizationFundação de Amparo à Pesquisa do Estado de São PauloFogarty International CenterNational Institute of Mental HealthPfizerAustralian GovernmentEuropean CommissionMinisterio de Salud de la NaciónAstraZenecaEli Lilly and Company
KeywordsHelpfulnessGeneralized anxiety disorderPsychiatryMental healthMedicineAnxietyClinical psychologyPsychologySocial psychology

Abstract

fetched live from OpenAlex

BACKGROUND: Treatment guidelines for generalized anxiety disorder (GAD) are based on a relatively small number of randomized controlled trials and do not consider patient-centered perceptions of treatment helpfulness. We investigated the prevalence and predictors of patient-reported treatment helpfulness for DSM-5 GAD and its two main treatment pathways: encounter-level treatment helpfulness and persistence in help-seeking after prior unhelpful treatment. METHODS: Data came from community epidemiologic surveys in 23 countries in the WHO World Mental Health surveys. DSM-5 GAD was assessed with the fully structured WHO Composite International Diagnostic Interview Version 3.0. Respondents with a history of GAD were asked whether they ever received treatment and, if so, whether they ever considered this treatment helpful. Number of professionals seen before obtaining helpful treatment was also assessed. Parallel survival models estimated probability and predictors of a given treatment being perceived as helpful and of persisting in help-seeking after prior unhelpful treatment. RESULTS: The overall prevalence rate of GAD was 4.5%, with lower prevalence in low/middle-income countries (2.8%) than high-income countries (5.3%); 34.6% of respondents with lifetime GAD reported ever obtaining treatment for their GAD, with lower proportions in low/middle-income countries (19.2%) than high-income countries (38.4%); 3) 70% of those who received treatment perceived the treatment to be helpful, with prevalence comparable in low/middle-income countries and high-income countries. Survival analysis suggested that virtually all patients would have obtained helpful treatment if they had persisted in help-seeking with up to 10 professionals. However, we estimated that only 29.7% of patients would have persisted that long. Obtaining helpful treatment at the person-level was associated with treatment type, comorbid panic/agoraphobia, and childhood adversities, but most of these predictors were important because they predicted persistence rather than encounter-level treatment helpfulness. CONCLUSIONS: The majority of individuals with GAD do not receive treatment. Most of those who receive treatment regard it as helpful, but receiving helpful treatment typically requires persistence in help-seeking. Future research should focus on ensuring that helpfulness is included as part of the evaluation. Clinicians need to emphasize the importance of persistence to patients beginning treatment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.201
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.052
GPT teacher head0.371
Teacher spread0.319 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations30
Published2021
Admission routes1
Has abstractyes

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