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Record W3193052986 · doi:10.21203/rs.3.rs-672967/v1

Past Gait Speed as an Independent Predictor of Mortality in Older Adults Beyond Current Gait Speed

2021· preprint· en· W3193052986 on OpenAlexaff
Joshua Solomon, J.‐G. Chabot, Philippe Desmarais, Marie‐France Forget, Quôc Dinh Nguyên

Bibliographic record

VenueResearch Square · 2021
Typepreprint
Languageen
FieldSocial Sciences
TopicHealth disparities and outcomes
Canadian institutionsCentre Hospitalier de l’Université de MontréalMcGill University
Fundersnot available
KeywordsGaitPreferred walking speedEffect of gait parameters on energetic costPhysical medicine and rehabilitationMedicineGait analysisHazard ratioConfidence intervalInternal medicine

Abstract

fetched live from OpenAlex

Abstract Background We investigated whether past values of gait speed in older adults provide additional prognostic information beyond current gait speed alone. We assessed various models to best describe past and current value for prediction. Methods We used data from the first five yearly rounds of the National Health and Ageing Trends Study, starting from 2011. The cohort consisted of 4289 community-dwelling participants aged 65 years and older. Gait speed was measured at baseline (Y1) and one year later (Y2). Three-year follow-up for mortality started in year 2. We estimated hazard ratios of various models using combinations of Y1 gait speed, Y2 gait speed, and change in gait speed from Y1 to Y2. Results The mean gait speed at year 2 was 0.77 m/s (0.26) and slightly increased by a mean of 0.04 m/s (0.20) from Y1 to Y2. A 0.1 m/s higher gait speed at Y2 was associated with decreased mortality (HR, 0.81 [0.78, 0.84]). Gait speed improvement from Y1 to Y2 decreased mortality (HR, 0.95 [0.92, 0.99] per 0.1 m/s increase). Models including both Y2 gait speed and change indicated that improvement in gait speed was associated with increased mortality (HR, 1.05 [1.00, 1.11]), independently of Y1 gait speed. Conclusions Past gait speed is predictive of mortality, independent of current gait speed, however, gait speed recovery does not completely negate mortality risks. Past gait speed information is a useful measure for risk prediction in older adults, but the direction of time is important for modelling and data interpretation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.010
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.021

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.010
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.091
GPT teacher head0.464
Teacher spread0.372 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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