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Record W3193720686

褐色細胞腫・パラガングリオーマ(PPGL)におけるMIBGを用いた診断・治療の最前線

2021· article· ja· W3193720686 on OpenAlexvenueno aff
絹谷 清剛

Bibliographic record

VenuePharma Medica · 2021
Typearticle
Languageja
FieldMedicine
TopicLymphoma Diagnosis and Treatment
Canadian institutionsnot available
Fundersnot available
KeywordsBusiness
DOInot available

Abstract

fetched live from OpenAlex

希少がんである褐色細胞腫・パラガングリオーマ(PPGL)に対して,これまでCVD化学療法が選択されることが多かったが,近年では131I-MIBG内照射療法への関心が高まっており,「褐色細胞腫・パラガングリオーマ診療ガイドライン2018」の診療アルゴリズムでは悪性PPGLの治療選択肢として国内未承認でありながら記載されている。また診断や褐色細胞腫・PPGLの診断や131I-MIBG内照射の適応判定では123I-MIBGシンチグラフィが重要な役割を果たしている。国内でこれらの診断・治療を実施する施設は限られているなか,20年以上前から先駆的に取り組んできた金沢大学医薬保健研究域医学系核医学教授の絹谷清剛先生に,現状と今後の展望について聞いた。

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.538
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0340.008

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.030
GPT teacher head0.319
Teacher spread0.289 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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