Bacterial Siderophore‐Binding Protein<scp>FepB</scp>
Bibliographic record
Abstract
Abstract Many bacteria can produce and secrete ferric‐iron‐specific chelators, called siderophores, to remove bound ferric iron from host proteins. The catecholate‐type siderophore enterobactin is a high‐affinity siderophore that is used by many Gram‐negative and Gram‐positive bacteria to acquire iron. In Gram‐negative bacteria, the ferric‐enterobactin (Fep) uptake system includes the outer membrane receptor FepA, the periplasmic binding protein (PBP) FepB, and the cytoplasmic membrane ABC transporter FepDG and FepC. FepB is a PBP with a type III structure fold, which has two independently folded domains linked together by a long α‐helix. This article will provide a comprehensive look at the structural and functional aspects of the 34 kDa PBP FepB.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.002 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".