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The ARTFL LEFFTDS Frontotemporal Lobar Degeneration (ALLFTD) Protocol: Preliminary Data and Future Plans (2081)

2020· article· en· W3194762624 on OpenAlexaff
Bradley F. Boeve, Adam L. Boxer, Howard Rosen, Leah K. Forsberg, Hilary W. Heuer, Danielle Brushaber, Brian S. Appleby, Joanna M. Biernacka, Yvette Bordelon, Hugo Botha, Patrick Brannelly, Bradford Dickerson, Susan Dickinson, Dennis W. Dickson, Kimiko Domoto‐Reilly, Kelley Faber, Anne M. Fagan, Julie A. Fields, Ann Fishman, Tatiana Foroud, Douglas Galasko, Ralitza H. Gavrilova, Tania Gendron, Daniel H. Geschwind, Nupur Ghoshal, Jill Goldman, Jonathan Graff‐Radford, Neill R. Graff‐Radford, Ian Grant, Murray Grossman, Ging‐Yuek Robin Hsiung, Eric J. Huang, Edward D. Huey, David J. Irwin, David T. Jones, Kejal Kantarci, Anna Karydas, Daniel Kaufer, David S. Knopman, Joel H. Kramer, Walter K. Kremers, John Kornak, Walter A. Kukull, Emma Lagone, Irene Litvan, Peter A. Ljubenkov, Diane Lucente, Ian R. Mackenzie, Masood Manoochehri, Joseph C. Masdeu, Scott McGinnis, Mario F. Mendez, Bruce Miller, Toji Miyagawa, K. Nelson, Chiadi U. Onyike, Alexander Pantelyat, Belén Pascual, Rodney Pearlman, Leonard Petrucelli, Rosa Rademakers, Eliana Marisa Ramos, Katherine P. Rankin, Katya Rascovsky, Jessica E. Rexach, Aaron Ritter, Erik D. Roberson, Julio Rojas -Martinez, Marwan N. Sabbagh, David P. Salmon, Rodolfo Savica, William W. Seeley, Adam M. Staffaroni, Jeremy A. Syrjanen, Maria Carmela Tartaglia, Nadine Tatton, Joanne Taylor, Arthur W. Toga, Sandra Weıntraub, Diana Wheaton, Bonnie Wong, Zbigniew K. Wszołek

Bibliographic record

VenueNeurology · 2020
Typearticle
Languageen
FieldMedicine
TopicTraumatic Brain Injury Research
Canadian institutionsToronto Western HospitalUniversity of TorontoUniversity of British Columbia
Fundersnot available
KeywordsGrossmanMillerArt historyArtPsychoanalysisPsychology

Abstract

fetched live from OpenAlex

To present background data and future plans on a newly funded protocol focused on sporadic and familial frontotemporal lobar degeneration (FTLD).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.034
metaresearch head score (Gemma)0.045
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Protocol · Consensus signal: none
Teacher disagreement score0.083
Threshold uncertainty score0.279

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0340.045
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0020.001
Science and technology studies0.0040.001
Scholarly communication0.0030.002
Open science0.0050.004
Research integrity0.0040.004
Insufficient payload (model declined to judge)0.0830.035

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.104
GPT teacher head0.357
Teacher spread0.253 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2020
Admission routes1
Has abstractyes

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