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Retinopathy of Prematurity (ROP) in high-risk babies and laser treatment

2021· article· en· W3194902070 on OpenAlexaff
Deep Bhardwaj, Shalu Aggarwal, Sadasivan Sitaraman, Kamlesh Khilnanai, Maha Singh

Bibliographic record

VenueIndian Journal of Health Sciences and Care · 2021
Typearticle
Languageen
FieldMedicine
TopicRetinopathy of Prematurity Studies
Canadian institutionsCanadian Paediatric Society
Fundersnot available
KeywordsRetinopathy of prematurityMedicinePediatricsGestational agePregnancyBiologyGenetics

Abstract

fetched live from OpenAlex

This study aimed to determine the proportion of babies having retinopathy of prematurity (ROP) by a screening of high-risk babies and to determine the proportion of babies requiring laser for ROP. A tertiary hospital-based prospective descriptive study was carried out over a span of 2 years in 370 neonates admitted in the Department of Neonatology for prematurity, low birth weight (less than 1750 g), or neonates weighing 1750–2000 g and having an unstable clinical course. Neonates with congenital anomalies e.g., congenital cataract, neonates whose ROP screening was postponed beyond inclusion time due to unstable clinical course, and neonates whose parents refused to give consent were excluded from the study. Retinal evaluation by indirect ophthalmoscopy was done in all subjects till the maturation of the retina. The development of ROP and the need for laser therapy were considered as unfavourable outcomes. Risk factors were assessed using univariate and multivariate analysis. ROP was detected in 147 cases (39.73%). Stage 1 ROP was present in 38 cases (25.85%); stage 2, 3, 4 and 5 ROP was found in 26(17.69%), 78(53.06%), 3(2.04%) and 2(1.36%) cases, respectively. Gender had no correlation to ROP (p value 0.107). Birth weight was a significant factor in the occurrence of ROP. Maternal gestational age at the time of birth is a significant factor for the development of ROP (p value <0.001). Prevalence of ROP is increasing due to improved survival of preterm babies. Adherence to a ROP screening protocol in neonatal care facilities can prevent blindness in a large number of infants by early diagnosis and treatment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.046
Threshold uncertainty score0.263

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.296
Teacher spread0.279 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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