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Record W3196558180 · doi:10.29169/1927-5129.2019.15.12

Protective Measures to Enhance Human Longevity and Aging: A Review of Strategies to Minimize Cellular Damage

2019· review· en· W3196558180 on OpenAlexaffvenue
Umesh Gupta, Gupta Sc

Bibliographic record

VenueJournal of Basic & Applied Sciences · 2019
Typereview
Languageen
FieldMedicine
TopicHydrogen's biological and therapeutic effects
Canadian institutionsAgriculture and Agri-Food Canada
Fundersnot available
KeywordsLongevitySenescenceOxidative damageDiseaseBiologyPhysiologyMedicineGerontologyEndocrinologyOxidative stressInternal medicineCell biology

Abstract

fetched live from OpenAlex

Aging is a universal process in all life forms. The most current and widely accepted definition of human aging is a progressive loss of function and energy production that is accompanied by decreased fertility and increased mortality with advancing age. The most obvious and commonly recognized consequence of aging and energy decline is a decrease in skeletal muscle function, which affects every aspect of human life from the ability to walk and run, to chew, and swallow and digest food. Some crucial factors responsible for aging and longevity include genetics, environment, and nutrition, serious disease disorders such as cancer and cardio-vascular diseases, sarcoma and cell senescence. Oxidative damage caused due to the accumulation of molecular waste-by-products of the body’s metabolic processes, which our bodies are unable to break down or excrete, is chiefly responsible for aging and diseases. Regular physical activity, consumption of foods rich in phytochemicals and anti-oxidants, cessation of smoking, avoiding foods high in saturated and hydrogenated fats are some of the strategies that should be taken into account to delay aging and prolong longevity.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.900
Threshold uncertainty score0.748

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0030.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.090
GPT teacher head0.401
Teacher spread0.312 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes2
Has abstractyes

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