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Record W3197135356 · doi:10.1051/e3sconf/202129203092

COVID-19: pathogenic mechanism, detection, and treatment

2021· article· en· W3197135356 on OpenAlexaff
Xiaoya Bai, Chenghao Li, Yueyan Li, Yujian Lin

Bibliographic record

VenueE3S Web of Conferences · 2021
Typearticle
Languageen
FieldMedicine
TopicCOVID-19 Clinical Research Studies
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsHydroxychloroquineCoronavirus disease 2019 (COVID-19)ChloroquineSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)LopinavirMechanism (biology)PneumoniaCoronavirusMedicine2019-20 coronavirus outbreakVirologyAdverse effectBetacoronavirusIntensive care medicineOutbreakImmunologyPharmacologyInternal medicineDisease

Abstract

fetched live from OpenAlex

COVID-19, which broke out in 2019 in China, is caused by SARS-CoV-2. According to the latest WHO real-time statistics, as of 1:19 p.m. BST on April 22, there were 142557268 cumulative new confirmed cases of coronavirus pneumonia and 3033798 cumulative deaths worldwide. Therefore, it is significant to understand the structure and the pathogenic mechanism of SARS-CoV-2, which is helpful to understand the diagnosis and treatment of sars-cov-2. We primarily investigate related sources on Pubmed and related scholar websites. We found some antiviral drugs such as lopinavir, chloroquine, and its derivative hydroxychloroquine, remdesivir, and arbidol have great potential in the treatment of COVID-19. However, some of them have a serious adverse reaction, reminding us to use them with caution.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.008
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.019
Threshold uncertainty score0.064

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.008
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0050.004
Science and technology studies0.0010.000
Scholarly communication0.0020.002
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0190.010

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.083
GPT teacher head0.408
Teacher spread0.325 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes1
Has abstractyes

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