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Record W3199630421 · doi:10.1530/ey.18.1.15

Clinical outcomes and complications of pituitary blastoma

2021· article· en· W3199630421 on OpenAlexafffund
Apy Liu, Kelsey MM, Nelly Sabbaghian, Park Sh, Deal CL, Esbenshade AJ, Oswald Ploner, Andrew C. Peet, Heidi Traunecker, Ahmed YHE, Margaret Zacharin, Anatoly Tiulpakov, Lapshina Am, Walter Aw, Parthapratim Dutta, Rai A, Márta Korbonits, de Kock L, Nichols KE, William D. Foulkes, Priest JR

Bibliographic record

VenueYearbook of pediatric endocrinology · 2021
Typearticle
Languageen
FieldMedicine
TopicPituitary Gland Disorders and Treatments
Canadian institutionsJewish General HospitalCentre Hospitalier Universitaire Sainte-JustineUniversité de MontréalMcGill University Health Centre
FundersCanadian Institutes of Health ResearchAmerican Lebanese Syrian Associated CharitiesMcGill University
KeywordsPulmonary BlastomaMedicineInternal medicine

Abstract

fetched live from OpenAlex

Here, the authors report the long−term outcomes of all 17 known, well−investigated cases of pituitary blastoma. The median age at diagnosis was 11 months, and the most frequent presentations were Cushing syndrome (n=10), cranial nerve palsies including ophthalmoplegia (n=7), reduced visual acuity (n=4), developmental delay (n=4), and symptoms of increased intracranial pressure (n=3). At a median follow−up of 6.7 years, 9 patients were alive. Chronic complications included neuroendocrine (n=8), visual (n=4), and neurodevelopmental (n=3) deficits. 16/17 cases were attributed to DICER1 abnormalities.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.334
Teacher spread0.302 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2021
Admission routes2
Has abstractyes

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