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Record W3201841574 · doi:10.30683/1929-2279.2019.08.10

Challenges in Development of Nanomedicine for Treatment of Cancer

2019· article· en· W3201841574 on OpenAlexvenueno aff
Dimple Chopra

Bibliographic record

VenueJournal of cancer research updates · 2019
Typearticle
Languageen
FieldMaterials Science
TopicNanoparticle-Based Drug Delivery
Canadian institutionsnot available
Fundersnot available
KeywordsNanomedicineCancer therapyCancerDrug deliveryMedicineCancer treatmentNanotechnologyMaterials scienceInternal medicineNanoparticle

Abstract

fetched live from OpenAlex

The inherent limitations of conventional cancer therapies have stimulated the growth of cancer nanomedicine. This is primarily attributable to its unique features for drug delivery, diagnosis and imaging, synthetic vaccine development and miniature medical devices, supplemented with the inherent therapeutic property of some nanomaterials. Nanotherapies that integrate some of these features are already in use and others have great potential in clinical development, with definitive results in near future. In order to develop smart cancer nanomedicine, it is very essential to bridge the gap between Bio-Nanoscience and Cancer Nanomedicine with a better understanding about the molecular basis of cancer. The development of smart cancer nanomedicine can be accelerated by patient stratification, rational drug selection, combination therapy, synergism with immunotherapeutics. The nanoplatforms that exhibit a significant increase in progression free survival are most desirable.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.039
Threshold uncertainty score0.538

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.136
GPT teacher head0.427
Teacher spread0.291 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes1
Has abstractyes

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