Set Membership Estimation with Dynamic Flux Balance Models
Why this work is in the frame
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Bibliographic record
Abstract
Dynamic flux balance models (DFBM) are used in this study to infer metabolite concentrations that are difficult to measure online. The concentrations are estimated based on few available measurements. To account for uncertainty in initial conditions the DFBM is converted into a variable structure system based on a multiparametric linear programming (mpLP) where different regions of the state space are described by correspondingly different state space models. Using this variable structure system, a special set membership-based estimation approach is proposed to estimate unmeasured concentrations from few available measurements. For unobservable concentrations, upper and lower bounds are estimated. The proposed set membership estimation was applied to batch fermentation of E. coli based on DFBM.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it