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Record W3204847446 · doi:10.1016/j.jbc.2021.101268

Convergent olfactory trace amine-associated receptors detect biogenic polyamines with distinct motifs via a conserved binding site

2021· article· en· W3204847446 on OpenAlexfundno aff
Liang Jia, Shengju Li, Wenxuan Dai, Lingna Guo, Zhengrong Xu, Anne M. Scott, Zhe Zhang, Jianfeng Ren, Qinghua Zhang, Thomas S. Dexheimer, Yu‐Wen Chung‐Davidson, Richard R. Neubig, Qian Li, Weiming Li

Bibliographic record

VenueJournal of Biological Chemistry · 2021
Typearticle
Languageen
FieldNeuroscience
TopicOlfactory and Sensory Function Studies
Canadian institutionsnot available
FundersFundamental Research Funds for the Central UniversitiesFisheries and Oceans CanadaCollege of Engineering, Michigan State UniversityU.S. Fish and Wildlife ServiceShanghai Jiao Tong UniversityGreat Lakes Fishery CommissionScience and Technology Commission of Shanghai MunicipalityShanghai Ocean UniversityNational Natural Science Foundation of ChinaShanghai Center for Brain Science and Brain-Inspired TechnologyMichigan State University
KeywordsCadaverineSperminePutrescineBiochemistryPolyamineBiogenic amineReceptorBiologySpermidineBinding siteLampreyG protein-coupled receptorChemistryOlfactionAmino acidStereochemistryNeurotransmitterNeuroscienceEnzyme

Abstract

fetched live from OpenAlex

OpenAlex records an abstract for this work, but it could not be fetched just now.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.023
Threshold uncertainty score0.889

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.109
GPT teacher head0.249
Teacher spread0.140 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations16
Published2021
Admission routes1
Has abstractyes

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