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The power of genetic diversity in genome-wide association studies of lipids

2021· review· en· 1,054 citations· W3205644245 on OpenAlex· 10.1038/s41586-021-04064-3

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.024
GPT teacher head0.322
Teacher spread
0.298 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Nature
Topic
Genetic Associations and Epidemiology
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
Université de MontréalUniversité du QuébecUniversity of TorontoUniversité LavalMontreal Heart Institute
Funders
National Institute of Diabetes and Digestive and Kidney DiseasesNational Heart, Lung, and Blood InstituteNational Center for Chronic Disease Prevention and Health PromotionNational Institute on AgingEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentEconomic and Social Research CouncilMedical Research CouncilNational Institutes of HealthCancer Research UKNovo Nordisk FondenLundbeckfondenPublic Health AgencyMcKnight FoundationBarts CharityOffice of Research and DevelopmentNational Cancer InstituteBritish Heart FoundationNational Human Genome Research InstituteWellcome TrustNational Institute for Health and Care ResearchU.S. Department of Veterans Affairs
Keywords
Genome-wide association studyGenetic diversityGenomeBiologyAssociation (psychology)Diversity (politics)GeneticsEvolutionary biologyGenetic associationComputational biologyGeneSingle-nucleotide polymorphismGenotypeMedicinePsychologyEnvironmental healthPopulationPolitical science
Has abstract in OpenAlex
no