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Record W3205690737 · doi:10.22215/etd/2019-14440

Characterization of Receptor Kinases and Downstream Signalling Components Involved in Fusarium Head Blight Resistance

2019· dissertation· en· W3205690737 on OpenAlexafffund
Nimrat Manes

Bibliographic record

Venuenot available
Typedissertation
Languageen
FieldAgricultural and Biological Sciences
TopicPlant-Microbe Interactions and Immunity
Canadian institutionsCarleton University
FundersAgriculture and Agri-Food Canada
KeywordsBiologyArabidopsisCell biologyMutantFusariumReceptorTransmembrane domainPlant disease resistanceGeneGenetics

Abstract

fetched live from OpenAlex

Fusarium Head Blight (FHB) is a devastating disease that affects wheat, barley and other small grain crops.Despite huge economic losses, current measures have not yielded desirable resistance to FHB.Resistance to F. graminearum is quantitative and thus identification of putative transmembrane receptors and signalling components involved in plant immunity will help combat this disease.A reverse genetic screen using 249 T-DNA Arabidopsis mutant plants identified two putative leucine-rich transmembrane localized receptors, RLK7 and APEX and a downstream signalling component, RbohF as contributors to FHB resistance.The expression analysis suggested that RLK7 and APEX activated distinct hormone signalling pathways, ethylene and salicylic acid, to mediate the resistance.Our analyses indicated that as an intracellular signalling component, RbohF integrates signals from these hormone signalling pathways to regulate stomatal pore closures, a potential entry point for the pathogen.Overall, our findings identified key genes involved in mediating quantitative resistance to F. graminearum.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.228
Teacher spread0.206 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes2
Has abstractyes

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