SERUM EXPRESSION OF MICRORNA-142 IN A COHORT OF BULGARIAN PATIENTS WITH INFLAMMATORY BOWEL DISEASES
Bibliographic record
Abstract
The study aims to assess the expression of serum miRNA-142_3p and miRNA-142_5p in IBD patients and its correlation with disease extent, activity and severity. It was performed on 35 patients with ulcerative colitis (UC), 35 patients with Crohn’s disease (CD) and 30 healthy controls. Serum miRNA-142 expression was assessed using reverse transcriptase quantitative real time PCR (RT-qPCR), and then correlated with that of a group of 30 healthy subjects. It was also correlated with disease extent and disease activity and severity indices (CDAI, Montreal classification, Partial Mayo score). The patients’ group showed mean serum miR-142_3p expression of 2.69±1.96 for CD, 1.66±0.90 for UC and 1.25±0.91 for the control group and serum miR-142_5p expression of 2.42±2.08 for CD, 1.61±1.12 for UC and 1.21±0.78 for the control group with a significant difference between groups. Conclusion: The expression of miR-142_3p and miR-142_5p was significantly higher in patients with CD compared to patients with UC and the control group.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".