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Record W3207001605 · doi:10.1101/2021.10.08.21264765

The impact of heating, ventilation, and air conditioning design features on the transmission of viruses, including the 2019 novel coronavirus: a systematic review of ventilation and coronavirus

2021· review· en· W3207001605 on OpenAlexafffund
Gail M. Thornton, Brian A. Fleck, Emily Kroeker, Dhyey Dandnayak, Natalie Fleck, Lexuan Zhong, Lisa Hartling

Bibliographic record

VenuemedRxiv · 2021
Typereview
Languageen
FieldMedicine
TopicInfection Control and Ventilation
Canadian institutionsUniversity of Alberta
FundersNatural Sciences and Engineering Research Council of CanadaCanadian Institutes of Health Research
KeywordsVentilation (architecture)HVACTransmission (telecommunications)Airborne transmissionAirflowCoronavirusAir conditioningEnvironmental scienceCoronavirus disease 2019 (COVID-19)MedicineEngineeringInternal medicineMechanical engineeringTelecommunications

Abstract

fetched live from OpenAlex

Abstract Aerosol transmission has been a pathway for virus spread for many viruses. Similarly, emerging evidence regarding SARS-CoV-2, and the resulting pandemic as declared by WHO in March 2020, determined aerosol transmission for SARS-CoV-2 to be significant. As such, public health officials and professionals have sought data regarding the effect of Heating, Ventilation, and Air Conditioning (HVAC) features to control and mitigate viruses, particularly coronaviruses. A systematic review was conducted using international standards to identify and comprehensively synthesize research examining the effectiveness of ventilation for mitigating transmission of coronaviruses. The results from 32 relevant studies showed that: increased ventilation rate was associated with decreased transmission, transmission probability/risk, infection probability/risk, droplet persistence, virus concentration, and increased virus removal and virus particle removal efficiency; increased ventilation rate decreased risk at longer exposure times; some ventilation was better than no ventilation; airflow patterns affected transmission; ventilation feature (e.g., supply/exhaust, fans) placement influenced particle distribution. Some studies provided qualitative recommendations; however, few provided specific quantitative ventilation parameters suggesting a significant gap in current research. Adapting HVAC ventilation systems to mitigate virus transmission is not a one-solution-fits-all approach but instead requires consideration of factors such as ventilation rate, airflow patterns, air balancing, occupancy, and feature placement. Practical Implications Increasing ventilation, whether through ventilation rates (ACH, m 3 /h, m 3 /min, L/min) or as determined by CO 2 levels (ppm), is associated with decreased transmission, transmission probability/risk, infection probability/risk, droplet persistence, and virus concentration, and increased virus removal and efficiency of virus particle removal. As well, professionals should consider the fact that changing ventilation rate or using mixing ventilation is not always the only way to mitigate and control viruses as varying airflow patterns and the use of ventilation resulted in better outcomes than situations without ventilation. Practitioners also need to consider occupancy, ventilation feature (supply/exhaust and fans) placement, and exposure time in conjunction with both ventilation rates and airflow patterns. Some recommendations with quantified data were made, including using an air change rate of 9 h -1 for a hospital ward; waiting six air changes or 2.5 hours before allowing different individuals into an unfiltered office with ∼2 fresh air changes (FCH) and one air change for a high-efficiency MERV or HEPA filtered laboratory; and using a pressure difference between -2 and -25 Pa in negative pressure isolation spaces. Other recommendations for practice included using or increasing ventilation, introducing fresh air, using maximum supply rates, avoiding poorly ventilated spaces, assessing fan placement and potentially increasing ventilation locations, and employing ventilation testing and air balancing checks.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.084
Threshold uncertainty score0.543

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.103
GPT teacher head0.397
Teacher spread0.293 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2021
Admission routes2
Has abstractyes

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