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Record W3207319257 · doi:10.1145/3484272.3484964

Machine learning pedagogy to support the research community

2021· article· en· W3207319257 on OpenAlex
Kevin Dick, Daniel G. Kyrollos, James R. Green

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetics, Bioinformatics, and Biomedical Research
Canadian institutionsCarleton University
Fundersnot available
KeywordsComputer scienceCurriculumUndergraduate researchDruggabilityOpen researchCompetition (biology)Cloud computingRanking (information retrieval)Data scienceArtificial intelligenceWorld Wide WebPedagogyMedical educationPsychology

Abstract

fetched live from OpenAlex

Machine learning methods are increasingly leveraged in disparate domains of research. Herein, we describe our curriculum design to introduce undergraduate students to applied research through a series of course assignments and a competition among peers to inspire other educators. We describe the overall course structure and detail how the assignments were tailored to a selected open research question while developing student understanding of machine learning. We outline the lessons learned from this new undergraduate curriculum design and describe how it may be adapted to similar courses. For the selected COVID19-related course-long problem of predicting which drugs might interact with specific proteins, we leveraged state-of-the-art tools for representing drug and protein sequences. We challenged students to develop unique solutions competitive with a current state-of-the-art model using reproducible Notebooks and cloud-based computing resources with the expectation that top-ranking solutions would be used to predict novel druggable targets within the SARS-CoV-2 proteome to possibly treat COVID19 patients. We motivate this curriculum design based on related competition frameworks that have led to notable research advancements and contributed to machine learning pedagogy. From our experience, the top student solutions were ultimately combined using a stacked classifier to create a publishable solution representing an actual research contribution. We highly recommend introducing undergraduate students to open research applications early in their program to encourage them to consider pursuing a career in research.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.676
Threshold uncertainty score0.606

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.093
GPT teacher head0.416
Teacher spread0.323 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it