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Metabolomics Differences of Glycine max QTLs Resistant to Soybean Looper

2021· article· en· 8 citations· W3207837394 on OpenAlex· 10.3390/metabo11100710

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Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
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All three models called this out of scope.

stratum: aff_core · design weight: 5595.24 (the sample is stratified; any rate computed without the weight is wrong)
Claude Opus 4.8OUT
genre: empirical
about Canada: no
confidence: high

Metabolomics of soybean insect resistance QTLs; a plant science question.

GPT-5.6 (high)OUT
genre: empirical
about Canada: no
confidence: high

The study investigates soybean metabolites and insect resistance.

Grok 4.5OUT
genre: empirical
about Canada: no
confidence: high

Plant metabolomics of insect-resistance QTLs in soybean is agricultural biology domain research.

Abstract

Quantitative trait loci (QTLs) E and M are major soybean alleles that confer resistance to leaf-chewing insects, and are particularly effective in combination. Flavonoids and/or isoflavonoids are classes of plant secondary metabolites that previous studies agree are the causative agents of resistance of these QTLs. However, all previous studies have compared soybean genotypes that are of dissimilar genetic backgrounds, leaving it questionable what metabolites are a result of the QTL rather than the genetic background. Here, we conducted a non-targeted mass spectrometry approach without liquid chromatography to identify differences in metabolite levels among QTLs E, M, and both (EM) that were introgressed into the background of the susceptible variety Benning. Our results found that E and M mainly confer low-level, global differences in distinct sets of metabolites. The isoflavonoid daidzein was the only metabolite that demonstrated major increases, specifically in insect-treated M and EM. Interestingly, M confers increased daidzein levels in response to insect, whereas E restores M's depleted daidzein levels in the absence of insect. Since daidzein levels do not parallel levels of resistance, our data suggest a novel mechanism that the QTLs confer resistance to insects by mediating changes in hundreds of metabolites, which would be difficult for the insect to evolve tolerance. Collective global metabolite differences conferred by E and M might explain the increased resistance of EM.

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The record

Venue
Metabolites
Topic
Soybean genetics and cultivation
Field
Agricultural and Biological Sciences
Canadian institutions
York University
Funders
Natural Sciences and Engineering Research Council of Canada
Keywords
DaidzeinIsoflavonoidQuantitative trait locusMetaboliteBiologyMetabolomicsAlleleIsoflavonesGenotypeGeneticsGlycineSecondary metaboliteGeneGenisteinBiochemistryFlavonoidBioinformaticsAmino acid
Has abstract in OpenAlex
yes