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Association of COVID-19 With Achieving Time-to-Surgery Benchmarks in Patients With Musculoskeletal Trauma

2021· article· en· W3209644377 on OpenAlexafffundabout
Ida Leah Gitajn, Paul M. Werth, Sheila Sprague, Nathan N. O’Hara, Gregory Della Rocca, Robert Zura, Meir Marmor, Christopher M. Domes, Lauren C. Hill, Christine Churchill, Christine E. Townsend, Chi Van, Natalie Hogan, Cara Girardi, Gerard P. Slobogean, Jeffrey Wells, Mohit Bhandari, Jean-Claude D’Alleyrand, Anthony Harris, Daniel C. Mullins, Lehana Thabane, Amber Wood, Gregory J. Della Rocca, Joan Hebden, Kyle J. Jeray, Lucas S. Marchand, Lyndsay M. O’Hara, Michael J. Gardner, Jenna Blasman, Jonah Davies, Stephen Y. Liang, Monica Taljaard, P.J. Devereaux, Gordon Guyatt, Diane Heels‐Ansdell, Debra Marvel, Jana Palmer, Jeff Friedrich, Frances Grissom, Saam Morshed, Robert V. O’Toole, Brad Petrisor, Megan Camara, Franca Mossuto, Manjari Joshi, Justin Fowler, Jessica Rivera, Max Talbot, Shannon Dodds, Alisha Garibaldi, Silvia Li, Uyen Nguyen, David Pogorzelski, Alejandra Rojas, Taryn Scott, Gina Del Fabbro, Olivia P. Szasz, Paula McKay, Andrea Howe, Joshua Rudnicki, Haley K. Demyanovich, Kelly Little, Adam Boissonneault, Michelle Medeiros, Genevieve Polk, Eric Kettering, Diamond Hale, Nirmen Mahal, Andrew Eglseder, Aaron J. Johnson, Christopher G. Langhammer, Christopher Lebrun, Theodore T. Manson, Jason W. Nascone, Ebrahim Paryavi, Raymond A. Pensy, Andrew N. Pollak, Marcus F. Sciadini, Yasmin Degano, Katherine Joseph, Heather Phipps, Eric Hempen, Herman Johal, Bill Ristevski, Dale Williams, Matthew Denkers, Krishan Rajaratnam, Jamal Al‐Asiri, Jordan Leonard, Francesc Marcano-Fernández, Jodi L. Gallant, Federico Pérsico, Marko Gjorgjievski, Annie George, Sarah M. McGaugh, Kaitlyn Pusztai, Sarah Piekarski, Mavis Lyons, Julia Gennaccaro, R Natoli, Greg E. Gaski, Todd O. McKinley, Walter W. Virkus, Anthony T. Sorkin, J. Szatkowski, Joseph R. Baele, Brian Mullis, Yohan Jang, Andrea Hudgins, Courteney L. Fentz, Maricela Diaz, Katelyn M. Garst, Emma W. Denari, Patrick M. Osborn, Sarah N. Pierrie, Eric Martínez, Joseph Kimmel, John D. Adams, Michael L. Beckish, Christopher C. Bray, Timothy R. Brown, Andrew W. Cross, Timothy Dew, Gregory K. Faucher, Richard W. Gurich, David E. Lazarus, S. John Millon, M. Jason Palmer, Scott E. Porter, Thomas M. Schaller, Michael S. Sridhar, L. Edwin Rudisill, Michael J. Garitty, Andrew S. Poole, Michael L. Sims, Robert Carlisle, Erin Adams-Hofer, Brandon S. Huggins, Michael D. Hunter, W. A. Marshall, Shea Bielby Ray, Cory D. Smith, Kyle M. Altman, Julia C. Bedard, Markus F. Loeffler, Erin R. Pichiotino, Austin A. Cole, Ethan J. Maltz, Wesley Parker, T. Bennett Ramsey, Alex Burnikel, Michael Colello, Russel Stewart, Jeremy Wise, Marion Moody, Matthew J. Anderson, Joshua Eskew, Benjamin N. Judkins, James M. Miller, Stephanie L. Tanner, Rebecca G. Snider, Kayla H. Pham, Abigail Martin, Emily Robertson, John Wilson Skyes, Utku Kandemir, Amir Matityahu, R. Trigg McClellan, Eric Meinberg, Theodore Miclau, David Shearer, Paul Toogood, Anthony Ding, Erin Donohue, Jothi Murali, Ashraf N. El Naga, Jennifer Tangtiphaiboontana, Tigist Belaye, Eleni Berhaneselase, Alexandra Paúl, Kartik Garg, Dimitry Pokhvashchev, Joshua L. Gary, Stephanie J. Warner, John W. Munz, Andrew M. Choo, Timothy S. Schor, Milton L. Chip Routt, Mayank Rao, Guillermo Pechero, Adam S. Miller, Michael Kutzler, Jennifer E. Hagen, Matthew Patrick, Richard Vlasak, Thomas Krupko, Kalia Sadasivan, Michael Talerico, MaryBeth Horodyski, Chris Koenig, Daniel P. Bailey, Daniel Wentworth, Justin T. Schwartz, Marissa Pazik, Niloofar Dehghan, Clifford B. Jones, Jessica Watson, Michael D. McKee, A Karim, Debra L. Sietsema, Alyse Williams, Tayler Dykes, William T. Obremsky, A. Alex Jahangir, Manish K. Sethi, Robert Boyce, Philip B. Mitchell, Daniel J. Stinner, Karen Trochez, Andrés Rodríguez, Vamshi Gajari, Elsa Rodriguez, Charles Pritchett, A. Fidel Moreno, Christina Boulton, Jason Lowe, Jason R. Wild, John T. Ruth, Michel Taylor, Brad Askam, Andrea Seach, Sabina Saeed, Hunter Culbert, Alejandro Francisco‐Cruz, Thomas R. Knapp, Colin Hurkett, Maya Lowney, Breanna Featherston, Michael J. Prayson, Indresh Venkatarayappa, Brandon Horne, Jennifer Jerele, Linda Clark, Montsant Jornet-Gibert, Laia Martínez-Carreres, David Martí-Garín, Jorge Serrano-Sanz, Joel Sánchez-Fernández, Matsuyama Sanz-Molero, Alejandro Carballo, Xavier Pelfort, Francesc Acerboni-Flores, Anna Alavedra-Massana, Neus Anglada-Torres, Alexandre Berenguer, Jaume Cámara-Cabrera, Ariadna Caparros-García, Ferran Fillat‐Gomà, Ruben Fuentes-López, Ramona Garcia-Rodriguez, Nuria Gimeno-Calavia, Guillem Graells-Alonso, Marta Martínez-Álvarez, Patricia Martínez-Grau, Raúl Pellejero-García, Ona Ràfols-Perramon, Juan Manuel Peñalver, Mònica Salomó Domènech, Albert Soler-Cano, Aldo Velasco-Barrera, Christian Yela‐Verdú, Mercedes Bueno-Ruiz, Estrella Sánchez-Palomino, Vito Andriola, Matilde Molina-Corbacho, Yeray Maldonado-Sotoca, Alfons Gasset-Teixidor, Jorge Blasco-Moreu, Núria Fernàndez-Poch, Josep Rodoreda-Puigdemasa, Arnau Verdaguer-Figuerola, Heber Enrique Cueva-Sevieri, Santiago García-Giménez, Ernesto Guerra-Farfán, Jordi Tomàs-Hernández, Jordi Teixidor-Serra, Vicente Molero-García, Jordi Selga-Marsá, Juan Antonio Porcel-Vasquez, José Vicente Andrés-Peiró, Joan Minguell-Monyart, Jorge H. Núñez, Maria del Mar Villar-Casares, Jaume Mestre-Torres, Pilar Lalueza-Broto, Felipe Moreira Borim, Yaiza Garcia‐Sanchez, Nicholas M. Romeo, Heather A. Vallier, Mary A. Breslin, Joanne Fraifogl, Eleanor S. Wilson, Leanne K. Wadenpfuhl, Paul G. Halliday, Isabella M. Heimke, Darius G. Viskontas, Kelly Apostle, Dory Boyer, Farhas O. Moola, Bertrand Perey, Trevor Stone, H. Michael Lemke, Mauri Zomar, Ella Spicer, Chen “Brenda” Fan, Krysten Payne, Kevin D. Phelps, Michael J. Bosse, Madhav A. Karunakar, Laurence B. Kempton, Stephen H. Sims, Joseph R. Hsu, Rachel B. Seymour, Claire Bartel, Robert Miles Mayberry, Maggie Brownrigg, Ada Mayfield, Juliette Sweeney, Hannah Pollock, Robert A. Hymes, Cary C. Schwartzbach, Jeff E. Schulman, Arjan Malekzadeh, Michael A. Holzman, Jonathan Wills, Lolita Ramsey, James S. Ahn, Farhanaz Panjshiri, Sharmistha Das, Antoinisha D. English, Sharon Haaser, Jaslynn Cuff, Holly Pilson, Eben A. Carroll, Jason J. Halvorson, Sharon Babcock, J. Brett Goodman, Martha B. Holden, Debra Bullard, Wendy R. Williams, Taylor Hill, Ariel Brotherton, Thomas F. Higgins, Justin M. Haller, David L. Rothberg, Ashley Neese, Mark Russell, Zachary M. Olsen, Abby V. McGowan, Sophia Hill, Marcus P. Coe, Kevin Dwyer, Devin S. Mullin, Clifford A. Reilly, Peter DePalo, Amy E. Hall, Rebecca E. Dabrowski, Theresa A. Chockbengboun, Marilyn Heng, Mitchel B. Harris, R. M. Smith, David W. Lhowe, John G. Esposito, Mira Bansal, Michael F. McTague, Ahmad Alnasser, Patrick F. Bergin, George V. Russell, Matthew L. Graves, John Morellato, Heather K. Champion, Leslie N. Johnson, Sheketha L. McGee, Eldrin Bhanat, Josny Thimothee, Jackie Serrano, Samir Mehta, Derek Donehan, Jaimo Ahn, Annamarie D. Horan, Mary Dooley, Ashley Kuczinski, Ashley Iwu, David A. Potter, Robert VanDemark, Branden Pfaff, Troy Hollinsworth, Kristi Atkins, Michael J. Weaver, Arvind von Keudell, Elizabeth Allen, Abigail E. Sagona, Todd Jaeblon, Robert Beer, Brent A. Bauer, Sean J. Meredith, Autumn Stone, Mark J. Gage, Rachel M. Reilly, Cindy Sparrow, Ariana Paniagua

Bibliographic record

VenueJAMA Health Forum · 2021
Typearticle
Languageen
FieldMedicine
TopicCOVID-19 and healthcare impacts
Canadian institutionsMcMaster University
FundersNational Institute of Arthritis and Musculoskeletal and Skin DiseasesCanadian Institutes of Health ResearchAgency for Healthcare Research and QualityMcMaster UniversityOsteosynthesis and Trauma Care FoundationStrykerHamilton Health SciencesPatient-Centered Outcomes Research InstituteU.S. Department of Defense
KeywordsCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakMedicineSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus InfectionsInternal medicineVirologyOutbreakDisease

Abstract

fetched live from OpenAlex

Importance In response to the COVID-19 pandemic, many hospital systems were forced to reduce operating room capacity and reallocate resources. The outcomes of these policies on the care of injured patients and the maintenance of emergency services have not been adequately reported. Objective To evaluate whether the COVID-19 pandemic was associated with delays in urgent fracture surgery beyond national time-to-surgery benchmarks. Design, Setting, and Participants This retrospective cohort study used data collected in the Program of Randomized Trials to Evaluate Preoperative Antiseptic Skin Solutions in Orthopaedic Trauma among at 20 sites throughout the US and Canada and included patients who sustained open fractures or closed femur or hip fractures. Exposure COVID-19–era operating room restrictions were compared with pre–COVID-19 data. Main Outcomes and Measures Surgery within 24 hours after injury. Results A total of 3589 patients (mean [SD] age, 55 [25.4] years; 1913 [53.3%] male) were included in this study, 2175 pre–COVID-19 and 1414 during COVID-19. A total of 54 patients (3.1%) in the open fracture cohort and 407 patients (21.8%) in the closed hip/femur fracture cohort did not meet 24-hour time-to-surgery benchmarks. We were unable to detect any association between time to operating room and COVID-19 era in either open fracture (odds ratio [OR], 1.40; 95% CI, 0.77-2.55;P = .28) or closed femur/hip fracture (OR, 1.01; 95% CI, 0.74-1.37;P = .97) cohorts. In the closed femur/hip fracture cohort, there was no association between time to operating room and regional COVID-19 prevalence (OR, 1.07; 95% CI, 0.70-1.64;P = .76). Conclusions and Relevance In this cohort study, there was no association between meeting time-to-surgery benchmarks in either open fracture or closed femur/hip fracture during the COVID-19 pandemic compared with before the pandemic. This is counter to concerns that the unprecedented challenges associated with managing the COVID-19 pandemic would be associated with clinically significant delays in acute management of urgent surgical cases and suggests that many hospital systems within the US were able to effectively implement policies consistent with time-to-surgery standards for orthopedic trauma in the context of COVID-19–related resource constraints.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.022
Threshold uncertainty score0.045

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.006
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.325
Teacher spread0.309 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations3
Published2021
Admission routes3
Has abstractyes

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