Bibliographic record
Abstract
Objective We sought to clarify if over-reactive mood in Generalized Anxiety Disorder (GAD) could be misdiagnosed as mood swings of Bipolar Disorder, or with affective instability in Borderline Personality Disorder. Methods We re-assessed 32 subjects who were referred to our clinic in 2020 and had been previously diagnosed with Bipolar and Borderline Personality Disorders, as they seem to fit more the diagnostic criteria of Generalized Anxiety Disorder (GAD), based on the structured clinical interview for DSM5 (SCID-DSM5) and our previously published general definition of this disorder. All the subjects met the DSM5 criteria of GAD and presented with excessive anxiety and worry lasting more than 6 months in different situations or spontaneous with no triggers, leading to dysfunctions in social, occupational, or any other important areas of the individual's life. The subjects also met our general definition of GAD and met the DSM5 diagnostic criteria for Social Anxiety Disorder, Panic Disorder and Major Depressive Disorder. Moreover some of these subjects had an over-reactive mood that was subjectively labeled by themselves as “mood swings”, but without any discreet hypomanic or manic episodes. Some of the subjects also described their mood as "unstable" that had led their previous clinicians with mislableing them with "affective instability" leading to the misdiagnosis of Borderline Personality Disorder. Results The result of the study showed that the over-reactive mood in GAD could simply by the patients be interpreted as mood swings and when reported to the physicians, diagnosed as Bipolar Disorder. In the same token the unstable mood in GAD could be taken as affective instability by the patients and the physicians, leading to the misdiagnosis of Borderline Personality Disorder. Other than mood over-reactivity and unstable mood in this sample that led their previous misdiagnoses with Bipolar and Borderline Personality Disorders, they were all presented with the symptoms of GAD like others without over-reactive and unstable mood. Conclusion The findings of our present adds a new symptom of over-reactive mood in GAD that could be easily misinterpreted as mood swings and affective instability and misdiagnosed as Bipolar and Borderline Personality Disorders.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".