MétaCan
Menu
Back to cohort
Record W3212152323 · doi:10.1093/jcag/gwab030

Crohn’s and Colitis Canada’s 2021 Impact of COVID-19 and Inflammatory Bowel Disease in Canada: Children and Expectant Mothers With Inflammatory Bowel Disease

2021· article· en· W3212152323 on OpenAlexafffundabout
Eric I. Benchimol, Matthew Carroll, Rose Geist, Anne M. Griffiths, James Guoxian Huang, David R. Mack, Çharles N. Bernstein, Alain Bitton, Jennifer Jones, Gilaad G. Kaplan, M Ellen Kuenzig, Kate Lee, Mariam S Mukhtar, Sanjay K. Murthy, Parul Tandon, Laura E. Targownik, Joseph W. Windsor, Cynthia H. Seow

Bibliographic record

VenueJournal of the Canadian Association of Gastroenterology · 2021
Typearticle
Languageen
FieldMedicine
TopicCOVID-19 Impact on Reproduction
Canadian institutionsCrohn's and Colitis CanadaInstitute for Clinical Evaluative SciencesUniversity of OttawaMcGill University Health CentreOttawa HospitalUniversity of ManitobaUniversity of AlbertaMount Sinai HospitalUniversity of CalgaryDalhousie UniversitySickKids FoundationUniversity of Toronto
FundersCanadian Institutes of Health ResearchTakeda CanadaPfizer CanadaSandoz CanadaMerck CanadaCrohn's and Colitis CanadaMylanGilead SciencesJanssen CanadaAmgen CanadaAbbVie CanadaAmgenPfizerEli Lilly and CompanyBristol-Myers Squibb
KeywordsMedicineInflammatory bowel diseasePandemicDiseaseDepression (economics)Ulcerative colitisAnxietyCrohn's diseaseMental healthCoronavirus disease 2019 (COVID-19)Intensive care medicineInternal medicinePsychiatry

Abstract

fetched live from OpenAlex

Coronavirus disease 2019 (COVID-19) in children with inflammatory bowel disease (IBD) typically results in a mild infection, similar to those without IBD. Children and adolescents have less severe manifestations of COVID-19 compared to older people, whether or not they have IBD. However, some IBD medications (in particular, corticosteroids) are associated with more severe COVID-19. During the first year of the global pandemic, more IBD care was provided with online technology, necessitated by efforts to reduce hospital and clinic visits. Additionally, non-endoscopic monitoring of inflammation has been required due to the cancellation of non-urgent procedures, resulting in longer endoscopy wait-times. In contrast, pregnant people (with and without IBD) who contract COVID-19 are at increased risk of severe manifestations, death and preterm delivery, making them a priority for severe acute respiratory syndrome coronavirus 2 protective measures and vaccination. Few studies have examined effect of COVID-19 on IBD-related disease activity in pregnant people with IBD. The pandemic has significantly affected the mental health and sense of well-being of children and their families, as well as pregnant people with IBD. These groups were much more likely to experience anxiety and depression compared with prior to the pandemic, even while concern has mostly abated regarding the effect of IBD medications and COVID-19 severity. Unfortunately, the availability of mental health care providers who specialize in people with IBD has not kept pace with the increasing demand.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.056
Threshold uncertainty score0.408

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.002
Science and technology studies0.0050.001
Scholarly communication0.0020.001
Open science0.0010.002
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0080.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.225
Teacher spread0.220 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2021
Admission routes3
Has abstractyes

Explore more

Same venueJournal of the Canadian Association of GastroenterologySame topicCOVID-19 Impact on ReproductionFrench-language works237,207