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Record W3212553226 · doi:10.1002/9781119413936.ch167

Radiation Therapy in Soft Tissue Sarcoma

2021· other· en· W3212553226 on OpenAlexaff
Anthony Bozzo, Aaron Gazendam, Kurt R. Weiss

Bibliographic record

VenueEvidence-Based Orthopedics · 2021
Typeother
Languageen
FieldMedicine
TopicSarcoma Diagnosis and Treatment
Canadian institutionsUniversity of TorontoMcMaster University
Fundersnot available
KeywordsMedicineSoft tissueMagnetic resonance imagingRadiation therapyAmputationSoft tissue sarcomaSarcomaThighSurgeryRadiologyAdverse effectPathologyInternal medicine

Abstract

fetched live from OpenAlex

This chapter presents a case scenario of a 50-year-old woman who presents with a growing mass in the medial thigh. Magnetic resonance imaging confirms a tumor with heterogeneous signal characteristics. Radiation therapy (XRT) is used in the management of soft tissue sarcomas (STS), with the goal of extending the virtual margin to the surrounding tissues. Limb-sparing surgery plus XRT is as effective as amputation for the local control of STS. XRT plus limb-sparing surgery is superior to surgery alone for the local control of high-grade extremity STS. Sarcomas are best treated by multidisciplinary teams and individualized treatment plans. There are potential advantages and disadvantages to both pre- and postoperative XRT. Multiple studies have demonstrated that preoperative XRT increases the probability of wound complications compared with postoperative XRT, which can cause adverse long-term functional consequences. The chapter provides recommendations for implementing evidence-based practice in the clinical setting.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.731
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0150.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.055
GPT teacher head0.332
Teacher spread0.277 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2021
Admission routes1
Has abstractyes

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Same venueEvidence-Based OrthopedicsSame topicSarcoma Diagnosis and TreatmentFrench-language works237,207