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Record W3214011348 · doi:10.5742/mewfm.2021.94159

Immune system response to the Covid 19 virus and 3rd boosters

2021· article· en· W3214011348 on OpenAlexfundno aff
Mark Spigelman

Bibliographic record

VenueWorld Family Medicine Journal /Middle East Journal of Family Medicine · 2021
Typearticle
Languageen
FieldMedicine
TopicSARS-CoV-2 and COVID-19 Research
Canadian institutionsnot available
FundersGrand Challenges CanadaKing Saud University
KeywordsVaccinationVirusCoronavirus disease 2019 (COVID-19)Immune systemMedicineVirologyImmunityIntensive care medicineImmunologyDiseaseInternal medicine

Abstract

fetched live from OpenAlex

A recent finding that the two-dose vaccination for the Covid-19 virus leads to a rapid loss of protection in many patients within 6 months. Thus the need for a 3rd injection has been found to be mandatory for continuing protection, as well as to highlight the need to monitor immune compromised patients and those with comorbidities particularly in indigenous populations where co-morbidities may be present preventing an adequate response to the initial vaccination. This has also highlighted the problem of lack of vaccines in the less developed parts of the world that requires urgent attention, as this is where new variants arise. The virus must be contained in these countries before we run out of letters in the Greek alphabet. Key words: Covid 19, virus, vaccines, 3rd injection, immunity, mutations, WHO

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.132
GPT teacher head0.366
Teacher spread0.234 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2021
Admission routes1
Has abstractyes

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