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Abstract 13863: Incidence and Clinical Significance of Cardiac Arrhythmias During Labor

2021· article· en· W3214917987 on OpenAlexaff
Nikhil Sharma, Kristie Coleman, Dillon Gurciullo, Rosaline Ma, Roland Hentz, Joanna Fishbein, Nirav Shah, Stavros Mountantonakis

Bibliographic record

VenueCirculation · 2021
Typearticle
Languageen
FieldMedicine
TopicCardiovascular Issues in Pregnancy
Canadian institutionsDillon Consulting
Fundersnot available
KeywordsMedicinePregnancyIncidence (geometry)Logistic regressionMedical recordNeonatal intensive care unitHeart diseaseMedical historyCardiac arrhythmiaClinical significanceIntensive care unitFamily historyPediatricsInternal medicineObstetricsAtrial fibrillation

Abstract

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Introduction: Physiologic changes during pregnancy can predispose mothers to new-onset cardiac arrhythmia. Women with a history of cardiac arrhythmia are at increased risk of recurrence or worsening of previously identified conditions. Previous studies have demonstrated that women with heart disease are at increased risk of maternal morbidity and mortality. However, few studies have explored the prevalence and clinical significance of maternal arrhythmias specifically. Objectives: The objectives of this study are to define the prevalence of arrhythmias in pregnancy and labor, identify risk factors for having such arrhythmias in patients both with and without prior history of cardiac arrhythmia, and examine the association between cardiac arrhythmias and adverse maternal outcomes. Methods: The medical records of patients admitted for delivery to any of the 13 hospitals in Northwell Health utilizing the electronic medical records from Jan 2012 - Dec 2020 were reviewed to identify patients with a history or current diagnosis of cardiac arrhythmia. Outcomes including Cesarean section, length of stay (LOS), infant requiring care in the neonatal intensive care unit (NICU) were evaluated between the arrhythmia group and a subset of deliveries without arrhythmias (controls). Results: Out of 141,772 patients, 88 were identified with a history of and/or current SVT and 87 were compared with 334 controls. The sample had mean age 31.7 ± 5.2 years, median length of stay 3 days (IQR 2-3), and median parity 2 (IQR 1-2). When adjusting for age and parity, logistic regression showed SVT was significantly associated with C-section (OR 1.9, CI 1.1-3.1, AUC 0.69 p=0.01). Fisher’s exact test showed SVT was associated with admission to NICU (p=0.03). Cox proportional hazards regression found SVT was not associated with LOS (HR 0.8, CI 0.6-1.0, p=0.06) when adjusted for age and parity. Conclusion: A history of SVT and/or current SVT during labor was associated with C-sections and NICU admissions but was not associated with LOS. These findings may help guide treatment strategies for this patient population.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.312
Teacher spread0.289 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2021
Admission routes1
Has abstractyes

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