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Record W3216709207 · doi:10.1038/s41592-021-01315-z

Micro-Meta App: an interactive tool for collecting microscopy metadata based on community specifications

2021· article· en· W3216709207 on OpenAlexaff
Alessandro Rigano, Shannon Ehmsen, Serkan Utku Öztürk, Joël Ryan, Alexander Balashov, Mathias Hammer, Koray Kırlı, Ulrike Boehm, Claire M. Brown, Karl Bellvé, James J. Chambers, Andrea Cosolo, Robert A. Coleman, Orestis Faklaris, Kevin E. Fogarty, Thomas Guilbert, Anna B. Hamacher, Michelle S. Itano, Daniel P. Keeley, Susanne Kunis, Judith Lacoste, Alex Laude, Y. Willa, Marco Marcello, Paula Montero Llopis, Glyn Nelson, Jaime A. Pimentel, Stefanie Weidtkamp‐Peters, Peter J. Park, B. Alver, David Grünwald, Caterina Strambio‐De‐Castillia

Bibliographic record

VenueNature Methods · 2021
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCell Image Analysis Techniques
Canadian institutionsMcGill University
FundersNational Institute of Biomedical Imaging and BioengineeringNational Institute of Neurological Disorders and StrokeNational Institute of General Medical SciencesRIKENIntellectual and Developmental Disabilities Research CenterNational Institute on Drug AbuseAgence Nationale de la RechercheDeutsche ForschungsgemeinschaftInfrastructures en Biologie Santé et AgronomieChan Zuckerberg InitiativeEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentSilicon Valley Community FoundationNational Cancer InstituteNational Institutes of HealthNational Science Foundation
KeywordsMetadataComputer scienceContext (archaeology)InteroperabilityVirtual microscopyQuality assuranceSoftwareWorld Wide WebEngineeringBiologyOperating system

Abstract

fetched live from OpenAlex

For quality, interpretation, reproducibility and sharing value, microscopy images should be accompanied by detailed descriptions of the conditions that were used to produce them. Micro-Meta App is an intuitive, highly interoperable, open-source software tool that was developed in the context of the 4D Nucleome (4DN) consortium and is designed to facilitate the extraction and collection of relevant microscopy metadata as specified by the recent 4DN-BINA-OME tiered-system of Microscopy Metadata specifications. In addition to substantially lowering the burden of quality assurance, the visual nature of Micro-Meta App makes it particularly suited for training purposes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.014
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.067
Threshold uncertainty score0.224

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0060.014
Meta-epidemiology (narrow)0.0030.002
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0060.002
Science and technology studies0.0010.001
Scholarly communication0.0040.004
Open science0.0030.008
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0670.031

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.065
GPT teacher head0.449
Teacher spread0.384 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations34
Published2021
Admission routes1
Has abstractyes

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