A Case of Coombs-Negative Hemolytic Anemia Prompting Diagnosis of SARS‐CoV‐2
Bibliographic record
Abstract
Case reports have discussed coronavirus disease of 2019 (COVID-19) patients presenting with hemolytic anemia, specifically with a positive direct antiglobulin test. However, Coombs-negative hemolytic anemia in COVID-19 patients has been rarely reported. We present an unusual case of Coombs-negative hemolytic anemia caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which responded with evidence-based COVID-19 treatments. We demonstrate the importance of considering SARS-CoV-2 as a cause of Coombs-negative hemolytic anemia, and we illustrate how treatment of the underlying COVID-19 illness, even if it is just supportive care, will help resolve the associated hemolysis.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".