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Record W3217764023 · doi:10.1093/eurheartj/ehab696

European Society of Cardiology guidance for the diagnosis and management of cardiovascular disease during the COVID-19 pandemic: part 1—epidemiology, pathophysiology, and diagnosis

2021· review· en· W3217764023 on OpenAlexfundno aff
Colin Baigent, Stephan Windecker, Daniele Andreini, Elena Arbelo, Emanuele Barbato, Antonio L. Bartorelli, Andreas Baumbach, Elijah R. Behr, Sérgio Berti, Héctor Bueno, Davide Capodanno, Riccardo Cappato, Alaide Chieffo, Jean‐Philippe Collet, Thomas Cuisset, Giovanni de Simone, Victoria Delgado, Paul Dendale, Dariusz Dudek, Thor Edvardsen, Arif Elvan, José Ramón González‐Juanatey, Mauro Gori, Diederick E. Grobbee, Tomasz J Guzik, Sigrun Halvorsen, Michael Haude, Hein Heidbüchel, Gerhard Hindricks, Borja Ibáñez, Nicole Karam, Hugo A. Katus, Stavros Konstantinides, Ulf Landmesser, Christophe Leclercq, Sergio Leonardi, Maddalena Lettino, Giancarlo Marenzi, Josepa Mauri, Marco Metra, Nuccia Morici, Christian Mueller, Anna Sonia Petronio, Marija Polovina, Tatjana Potpara, Fabien Praz, Bernard Prendergast, Eva Prescott, Susanna Price, Piotr Pruszczyk, Oriol Rodríguez‐Leor, Marco Roffi, Rafael Romaguera, Stephan Rosenkranz, Andrea Sarkozy, Martijn Scherrenberg, Petar Seferovic, Michele Senni, Francesco Raffaele Spera, Giulio Stefanini, Hölger Thiele, Daniela Tomasoni, Rhian M. Touyz, Arthur A.M. Wilde, Bryan Williams

Bibliographic record

VenueEuropean Heart Journal · 2021
Typereview
Languageen
FieldMedicine
TopicCOVID-19 Clinical Research Studies
Canadian institutionsnot available
FundersBiosense WebsterAmsterdam Cardiovascular Sciences, Amsterdam University Medical CentersAbbott VascularHumanitas Research HospitalUniversitair Ziekenhuis AntwerpenCentre Hospitalier Universitaire de RennesMicroPortBerlin Institute of HealthIdorsia PharmaceuticalsSt George's University Hospitals NHS Foundation TrustUniversidade de Santiago de CompostelaUniversiteit HasseltHumanitas UniversityBracco ImagingUniversität zu KölnUniversiteit AntwerpenUniversità di PisaTrakya ÜniversitesiUniwersytet WarszawskiServierUniversità degli Studi di BresciaCentro Nacional de Investigaciones CardiovascularesUniversitat de BarcelonaJohannes Gutenberg-Universität MainzLeids Universitair Medisch CentrumUniversità degli Studi di PaviaSchweizerische HerzstiftungNovo NordiskAmsterdam University Medical CentersWarszawski Uniwersytet MedycznyDipartimento di Scienze Biomediche Avanzate, Università degli Studi di Napoli Federico IIUniversiteit van AmsterdamZonMwDeutsches Zentrum für Herz-KreislaufforschungCanada Excellence Research Chairs, Government of CanadaUniversity of GlasgowSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen ForschungCleveland ClinicUniversiteit LeidenInstitut National de la Santé et de la Recherche MédicaleNational Cancer InstituteUniversity College LondonHôpitaux Universitaires de GenèveBritish Heart FoundationUniversitetet i OsloCardinal HealthMedicureInfraRedxAcceleronImperial College LondonGeneralitat de CatalunyaSerbian Academy of Sciences and ArtsPfizerUniversità degli Studi di MilanoRegeneron PharmaceuticalsBoston Scientific CorporationUniversität BaselBristol-Myers SquibbCentro de Investigación Biomédica en Red Enfermedades CardiovascularesUniversità di CataniaAbiomedSanofiUnited Therapeutics CorporationBayerUniwersytet Jagielloński Collegium MedicumNational Institute for Health and Care ResearchQueen Mary University of LondonCSL BehringEli Lilly and CompanyGrupo Ferrer Internacional, S.AAstraZenecaEdwards LifesciencesEuropean Society of CardiologyAmgenDaiichi Sankyo EuropeSt. Jude MedicalYale UniversityNational Science Foundation
KeywordsMedicinePandemicEpidemiologyCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PathophysiologyIntensive care medicineDiseaseCardiologyInternal medicinePathologyInfectious disease (medical specialty)Outbreak

Abstract

fetched live from OpenAlex

AIMS: Since its emergence in early 2020, the novel severe acute respiratory syndrome coronavirus 2 causing coronavirus disease 2019 (COVID-19) has reached pandemic levels, and there have been repeated outbreaks across the globe. The aim of this two-part series is to provide practical knowledge and guidance to aid clinicians in the diagnosis and management of cardiovascular disease (CVD) in association with COVID-19. METHODS AND RESULTS: A narrative literature review of the available evidence has been performed, and the resulting information has been organized into two parts. The first, reported here, focuses on the epidemiology, pathophysiology, and diagnosis of cardiovascular (CV) conditions that may be manifest in patients with COVID-19. The second part, which will follow in a later edition of the journal, addresses the topics of care pathways, treatment, and follow-up of CV conditions in patients with COVID-19. CONCLUSION: This comprehensive review is not a formal guideline but rather a document that provides a summary of current knowledge and guidance to practicing clinicians managing patients with CVD and COVID-19. The recommendations are mainly the result of observations and personal experience from healthcare providers. Therefore, the information provided here may be subject to change with increasing knowledge, evidence from prospective studies, and changes in the pandemic. Likewise, the guidance provided in the document should not interfere with recommendations provided by local and national healthcare authorities.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.016
metaresearch head score (Gemma)0.024
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.881
Threshold uncertainty score0.984

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0160.024
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0030.003
Bibliometrics0.0000.000
Science and technology studies0.0010.002
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.353
GPT teacher head0.486
Teacher spread0.133 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations145
Published2021
Admission routes1
Has abstractyes

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