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Record W347658325

Commercialization of Health Products from Sub-Saharan Africa: Challenges and Opportunities

2011· dissertation· en· W347658325 on OpenAlexfundno aff
Kenneth Simiyu

Bibliographic record

VenueTSpace (University of Toronto) · 2011
Typedissertation
Languageen
FieldMedicine
TopicBiotechnology and Related Fields
Canadian institutionsnot available
FundersCanadian Institutes of Health Research
KeywordsCommercializationLife expectancyProduct (mathematics)BusinessEconomic growthDiversification (marketing strategy)New product developmentPolitical scienceMarketingMedicineEnvironmental healthPopulationEconomics
DOInot available

Abstract

fetched live from OpenAlex

Despite the global progress made in improving health of people and increasing the life expectancy, Sub-Saharan Africa continues to be plagued by many health problems. Commercialization of health products from Sub-Saharan Africa presents opportunities to solve some of these health problems as well as generate economic returns. This thesis explored science based health product commercialization in sub-Saharan Africa through three studies. The objective was to identify opportunities and challenges facing health product commercialization in Sub-Saharan Africa. A qualitative case study approach was used and data collected using interviews. The first study involved looking at science based health product commercialization at a national level. Rwanda was chosen for this study. Thirty eight key informants selected from various institutions that form the health innovation system in Rwanda were interviewed. The results of the study show that opportunities exist in Rwanda for health product commercialization mainly because of the strong political will to support health innovation. However the main challenge is that there are no linkages between the actors involved in health innovation in Rwanda. The second study looked at health innovation at the level of a research institution. The Kenya Medical Research Institute (KEMRI) was studied where eight key informants were interviewed. The results show that KEMRI faced many challenges in its attempt at health product development, including shifting markets, lack of infrastructure, inadequate financing, and weak human capital with respect to innovation. However, it overcame them through diversification, partnerships and changes in culture. The third study looked at health technologies that are being developed in sub-Saharan Africa but have stagnated in laboratories. Thirty nine key informants were interviewed. A total of 25 technologies were identified, the majority being traditional plant medicines; other technologies identified included diagnostic tests and medical devices. Many of these technologies require further validation. Other key challenges to commercialization of these technologies that were identified included a lack of innovative culture amoung scientists and policy makers and lack of proof of concept funds including venture capital. Overall, this thesis identified opportunities for science based health commercialization in Africa, and also provides recommendations on how to overcome major challenges.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesResearch integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.805
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0020.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.071
GPT teacher head0.259
Teacher spread0.188 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designOther design
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2011
Admission routes1
Has abstractyes

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