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Record W35465265 · doi:10.1159/000468136

Treatment of Intractable Depression

2017· article· en· W35465265 on OpenAlexaff
J. Ananth, R. Ruskin

Bibliographic record

VenueInternational Pharmacopsychiatry · 2017
Typearticle
Languageen
FieldMedicine
TopicElectroconvulsive Therapy Studies
Canadian institutionsSt Mary's Hospital Centre
Fundersnot available
KeywordsMedicineDepression (economics)Refractory (planetary science)Electroconvulsive therapyPsychiatryPharmacotherapyAntidepressantIntensive care medicineSchizophrenia (object-oriented programming)Anxiety

Abstract

fetched live from OpenAlex

Depression is a frequently encountered psychiatric disorder. Current methods of treatment of these syndromes range from psychotherapy, pharmacotherapy, electroconvulsive therapy and in severe refractory cases, lobotomy. Despite the usefulness of all these methods, 10-28 % of the depressed patients remain refractory to treatment (Bratfos and Haug, 1968; Greenblatt et al, 1964; Smith et al, 1969). As suicide is a relatively high risk in depressed patients, refractory patients may run even higher risk. Hence, various workers have attempted to enhance the antidepressant effects of medications by different techniques. As the basis of all these techniques remain hypothetical at this time, the conclusive evidence of the effectiveness of these methods can come from the clinical application of these techniques by the physicians in treating their intractable, depressed patients.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.003
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.394
Teacher spread0.369 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations12
Published2017
Admission routes1
Has abstractyes

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