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Record W4200148845 · doi:10.1016/j.watres.2021.117997

Tenets of a holistic approach to drinking water-associated pathogen research, management, and communication

2021· review· en· W4200148845 on OpenAlexaff
Caitlin R. Proctor, Emily Garner, Kerry A. Hamilton, Nicholas J. Ashbolt, Lindsay J. Caverly, Joseph O. Falkinham, Charles N. Haas, Michèle Prévost, D. Rebecca Prevots, Amy Pruden, Lutgarde Raskin, Janet E. Stout, Sarah–Jane Haig

Bibliographic record

VenueWater Research · 2021
Typereview
Languageen
FieldMedicine
TopicMycobacterium research and diagnosis
Canadian institutionsPolytechnique Montréal
FundersNHLBI Division of Intramural ResearchDivision of Intramural Research, National Institute of Allergy and Infectious DiseasesUniversity of PittsburghNational Institute of Allergy and Infectious DiseasesNational Institutes of HealthWater Research Foundation
KeywordsSanitationPremiseBusinessUnintended consequencesEnvironmental resource managementLegionnaires' diseaseRisk analysis (engineering)Nontuberculous mycobacteriaLegionellaEnvironmental planningBiologyLegionella pneumophilaEngineeringMycobacteriumGeographyEnvironmental scienceEnvironmental engineeringPolitical science

Abstract

fetched live from OpenAlex

In recent years, drinking water-associated pathogens that can cause infections in immunocompromised or otherwise susceptible individuals (henceforth referred to as DWPI), sometimes referred to as opportunistic pathogens or opportunistic premise plumbing pathogens, have received considerable attention. DWPI research has largely been conducted by experts focusing on specific microorganisms or within silos of expertise. The resulting mitigation approaches optimized for a single microorganism may have unintended consequences and trade-offs for other DWPI or other interests (e.g., energy costs and conservation). For example, the ecological and epidemiological issues characteristic of Legionella pneumophila diverge from those relevant for Mycobacterium avium and other nontuberculous mycobacteria. Recent advances in understanding DWPI as part of a complex microbial ecosystem inhabiting drinking water systems continues to reveal additional challenges: namely, how can all microorganisms of concern be managed simultaneously? In order to protect public health, we must take a more holistic approach in all aspects of the field, including basic research, monitoring methods, risk-based mitigation techniques, and policy. A holistic approach will (i) target multiple microorganisms simultaneously, (ii) involve experts across several disciplines, and (iii) communicate results across disciplines and more broadly, proactively addressing source water-to-customer system management.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.012
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.944
Threshold uncertainty score0.899

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0120.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0020.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.004
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.356
GPT teacher head0.481
Teacher spread0.125 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations53
Published2021
Admission routes1
Has abstractyes

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