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Record W4200199436 · doi:10.1136/bmjopen-2021-053857

Assessing the impact of screening, early identification and intervention programmes for chronic kidney disease: protocol for a scoping review

2021· review· en· W4200199436 on OpenAlexaff
Ikechi G. Okpechi, Fergus Caskey, Abduzhappar Gaipov, Elliot Koranteng Tannor, Laura Hamonic, Gloria Ashuntantang, Jo‐Ann Donner, Ana Elizabeth Figueiredo, Reiko Inagi, Magdalena Madero, Charu Malik, Monica Moorthy, Roberto Pecoits‐Filho, Vladimı́r Tesař, Adeera Levin, Vivekanand Jha

Bibliographic record

VenueBMJ Open · 2021
Typereview
Languageen
FieldMedicine
TopicChronic Kidney Disease and Diabetes
Canadian institutionsUniversity of British ColumbiaUniversity of Alberta
FundersNovo NordiskFresenius Medical Care North AmericaAkebia TherapeuticsGlaxoSmithKlineAstraZeneca
KeywordsMedicineProtocol (science)Kidney diseaseIntervention (counseling)Identification (biology)Public healthDiseaseAlternative medicineHealth services researchEpidemiologyFamily medicineNursingInternal medicinePathology

Abstract

fetched live from OpenAlex

INTRODUCTION: Chronic kidney disease (CKD) is a major threat to public health, especially in low-income and lower middle-income countries, where resources for treating patients with advanced CKD are scarce. Although early CKD identification and intervention hold promise for reducing the burden of CKD and risk factors, it remains unclear if an uniform strategy can be applicable across all income groups. The aim of this scoping review is to synthesise available evidence on early CKD identification programmes in all world regions and income groups. The study will also identify efforts that have been made to use interventions and implementation of early identification programmes for CKD across countries and income groups. METHODS AND ANALYSIS: This review will be guided by the methodological framework for conducting scoping studies developed by Arksey and O'Malley. Empirical (Medline, Embase, Cochrane Library, CINAHL, ISI Web of Science and PsycINFO) and grey literature references will be searched to identify studies on CKD screening, early identification and interventions across all populations. Two reviewers will independently screen references in consecutive stages of title/abstract screening and then full-text screening. We will use a general descriptive overview, tabular summaries and content analysis on extracted data. ETHICS AND DISSEMINATION: The findings from our planned scoping review will enable us to identify items in early identification programmes that can be used in developing screening toolkits for CKD. We will disseminate our findings using traditional approaches that include open-access peer-reviewed publication, scientific presentations and a white paper (call to action) report. Ethical approval will not be required for this scoping review as the data will be extracted from already published studies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.123
metaresearch head score (Gemma)0.115
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.123
Threshold uncertainty score0.652

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1230.115
Meta-epidemiology (narrow)0.0060.007
Meta-epidemiology (broad)0.0130.018
Bibliometrics0.0140.016
Science and technology studies0.0060.006
Scholarly communication0.0100.010
Open science0.0070.009
Research integrity0.0090.009
Insufficient payload (model declined to judge)0.0830.017

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.231
GPT teacher head0.594
Teacher spread0.363 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSystematic review
Domainnot available
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2021
Admission routes1
Has abstractyes

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