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Record W4200414824 · doi:10.1097/md9.0000000000000199

Superior mesenteric vein thrombosis in a patient with primary focal segmental glomerulosclerosis

2021· article· en· W4200414824 on OpenAlexaff
Mohammed Somaili, Carol Chunfeng Wang, Omar Almansour, Basma Alrefa’ei

Bibliographic record

VenueMedicine Case Reports and Study Protocols · 2021
Typearticle
Languageen
FieldMedicine
TopicVascular anomalies and interventions
Canadian institutionsWestern University
Fundersnot available
KeywordsMedicineNephrotic syndromeFocal segmental glomerulosclerosisMinimal change diseaseAsymptomaticRenal vein thrombosisThrombosisPrednisoneMembranous nephropathyAbdominal painSurgerySuperior mesenteric veinRenal biopsyRadiologyInternal medicineGlomerulonephritisBiopsyKidney

Abstract

fetched live from OpenAlex

Abstract Introduction: Nephrotic syndrome creates a hypercoagulable state that predisposes patients to venous thromboembolism. Mesenteric vein thrombosis associated with minimal change disease and membranous nephropathy has rarely been reported. Few cases of mesenteric vein thrombosis have been reported in some types of nephrotic syndrome; however, isolated mesenteric vein thrombosis has not been previously reported in adults with nephrotic syndrome due to focal segmental glomerulosclerosis. Patient concern: A 19-year-old man with biopsy-proven primary focal segmental glomerulosclerosis was in partial disease remission when he presented with postprandial abdominal pain four months after starting prednisone therapy. Diagnosis: Abdominal computed tomography revealed subacute superior mesenteric vein thrombosis complicated by distal ileum ischemia. Intervention: The patient was treated with low-molecular-weight heparin and bridged with warfarin. Prednisone therapy was continued for the underlying nephrotic syndrome. Outcomes: The patient's symptoms improved with conservative management. He continued to be asymptomatic at subsequent follow-up visits, with no reported complications or medication side effects. Conclusion: This unique case of superior mesenteric vein thrombosis in an adult with nephrotic syndrome due to primary focal segmental glomerulosclerosis in partial remission diagnosed on computed tomography was treated conservatively with anticoagulation therapy. The findings in this case suggest that in patients with nephrotic syndrome, hypercoagulability may extend beyond the acute stage of the disease despite treatment.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.086
Threshold uncertainty score0.600

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.035
GPT teacher head0.326
Teacher spread0.291 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2021
Admission routes1
Has abstractyes

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