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Record W4200476855 · doi:10.1139/er-2021-0092

Progress of optical biosensors for analyzing pathogens and organic pollutants in water since 2015

2021· article· en· W4200476855 on OpenAlexafffundvenue
Bo Liu, Xing Song, Weiyun Lin, Yan Zhang, Bing Chen, Baiyu Zhang

Bibliographic record

VenueEnvironmental Reviews · 2021
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicAdvanced biosensing and bioanalysis techniques
Canadian institutionsMemorial University of Newfoundland
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsBiosensorPollutantContext (archaeology)NanotechnologyAptamerHuman healthBiochemical engineeringContaminationEnvironmental scienceEnvironmental chemistryChemistryBiologyMaterials scienceEcologyEngineering

Abstract

fetched live from OpenAlex

Contamination of water with pathogens and organic pollutants is one of the major environmental problems posing a risk to human health. Climate change with extreme weather events exacerbates this problem. The ability to monitor pollutants in a fast, continuous, and accurate manner is in increasing demand, especially under the climate change context, but is challenged by their ubiquity and trace concentrations. Optical biosensing is an attractive solution, owing to its rapid and accurate detection with high sensitivity. Principally, an optical biosensor recognizes bioactive toxins and contaminants via tailored bioreceptors (e.g., aptamers, enzymes, and cells) and transduces the biological response to optical signals. Research efforts have focused on tailoring bioreceptors and enhancing signal transduction by nanoparticles. This study comprehensively reviewed the mechanisms for optical biosensing and the recent development of bioreceptors and nanomaterials that enhance the rapid, easy, and accurate analysis of emerging contaminants in water. The advantages and challenges for the sensitivity, selectivity, and durability of biosensors are discussed, together with the opportunities and development strategies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.029
Threshold uncertainty score0.329

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.276
Teacher spread0.266 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2021
Admission routes3
Has abstractyes

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