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Record W4200598941 · doi:10.21203/rs.3.rs-1206247/v1

Safety and Long-term Improvement of Mesenchymal Stromal Cell Infusion in Critically COVID-19 Patients: A Randomized Clinical Trial.

2021· preprint· en· W4200598941 on OpenAlexfundno aff
Cármen Lúcia Kuniyoshi Rebelatto, Alexandra Cristina Senegaglia, Cláudio Luciano Franck, Débora Regina Daga, Patrícia Shigunov, Marco Augusto Stimamiglio, Daniela Boscaro Marsaro, Bruna Schaidt, Andressa Micosky, Ana Paula de Azambuja, Cleverson Alex Leitão, Ricardo Rasmussen Petterle, Valderez Ravaglio Jamur, Isadora May Vaz, Antônio Paulo Mallmann, Hipólito Carraro, Eduardo Ditzel, Paulo Roberto Slud Brofman, Alejandro Correa

Bibliographic record

VenueResearch Square · 2021
Typepreprint
Languageen
FieldMedicine
TopicMesenchymal stem cell research
Canadian institutionsnot available
FundersUniversidade Federal do ParanáOffice of Energy Research and DevelopmentMinistério da SaúdeConselho Nacional de Desenvolvimento Científico e Tecnológico
KeywordsCoronavirus disease 2019 (COVID-19)Mesenchymal stem cellTerm (time)MedicineIntensive care medicineCritically illRandomized controlled trial2019-20 coronavirus outbreakClinical trialInternal medicineVirologyPathologyPhysicsOutbreakDisease

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.032
metaresearch head score (Gemma)0.063
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow), Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.092
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0320.063
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0030.001
Bibliometrics0.0010.001
Science and technology studies0.0000.002
Scholarly communication0.0000.000
Open science0.0010.005
Research integrity0.0010.005
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.104
GPT teacher head0.479
Teacher spread0.375 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2021
Admission routes1
Has abstractno

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