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Record W4205225366 · doi:10.1111/vox.13130

International Forum on Policies and Practice for Transfusion of <scp>ABO</scp> and <scp>RhD</scp> Non‐Identical Platelets: Responses

2021· article· en· W4205225366 on OpenAlexaff
Rebecca Cardigan, Helen V. New, Lise J Estcourt, Е Б Жибурт, Rounak Dubey, Jesper Bengtsson, Magnus Jöud, Carlos Castillo, Joan Cid, Miquel Lozano, Dhana Gounder, Peter Flanagan, Sarah L. Morley, Gwen Clarke, Dana V. Devine, Salwa Hindawi, Aqeel AlOtaibi, Carolina Bonnet Bub, José Mauro Kutner, Toshiyuki Ikeda, Naoko Goto, Hitoshi Okazaki, Magali J. Fontaine, Jeremiah Pasion, Linda Song, Tom Latham, Jean‐Louis Kerkhoffs, Masja de Haas, Jaap Jan Zwaginga, Birgit Gathof, Katharina Ommer, France Pirenne, Michel Raba, Anne Isabelle François, James Daly, Tanya Powley, Nancy M. Dunbar

Bibliographic record

VenueVox Sanguinis · 2021
Typearticle
Languageen
FieldMedicine
TopicBlood groups and transfusion
Canadian institutionsCanadian Blood Services
Fundersnot available
KeywordsABO blood group systemPlateletABO incompatibilityMedicineImmunology

Abstract

fetched live from OpenAlex

Question 1We have apheresis (70%) and whole blood derived (buffy coat) (30%).Each pool is derived from four to five donors.Whole blood processing is mostly manual.Platelets are suspended in plasma or in SSP+ [1].Рlatelets for neonates/infant transfusion have the same specification as those for adults but more often are irradiated [2]. Question 2According to our national/governmental guide:• Transfusion of platelet concentrate non-identical in the ABO system is allowed, obtained using an additional solution;• Transfusion of whole-blood derived platelet concentrates from a blood units of group O or apheresis platelet concentrates AB group to a recipient with any blood group is allowed.• 21% platelet transfusions are ABO non-identical. Question 3Among those mentioned strategies only storage of platelets in PAS is used to mitigate the risk of haemolytic transfusion reactions due to ABO incompatibility.Plasma transfusion of the AB group to the recipient with any blood group is allowed Question 4 I did not observe cases of haemolytic transfusion reactions to platelets, and no such cases reported in national haemovigilance scheme. Question 5According our national/governmental guide, the compatibility of the donor and adult recipient in terms of red blood cell antigens D, C, c, E, e, K is not taken into account when transfusing platelet concentrates obtained using apheresis or using an additional solution or pathogen-reduced platelet concentrate.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.040
metaresearch head score (Gemma)0.058
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.065
Threshold uncertainty score0.210

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0400.058
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.003
Bibliometrics0.0010.002
Science and technology studies0.0030.003
Scholarly communication0.0080.005
Open science0.0050.007
Research integrity0.0650.027
Insufficient payload (model declined to judge)0.0380.016

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.311
Teacher spread0.292 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2021
Admission routes1
Has abstractyes

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