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Record W4205327515 · doi:10.1002/0470846429.ch2

The Clinical Syndrome and the Biochemical Definition

2001· other· en· W4205327515 on OpenAlexaff
Jean-Marie Ékoé, Paul Zimmet

Bibliographic record

Venuenot available
Typeother
Languageen
FieldMedicine
TopicDiabetes, Cardiovascular Risks, and Lipoproteins
Canadian institutionsCentre Hospitalier de l’Université de Montréal
Fundersnot available
KeywordsDiabetes mellitusMedicineInsulinPopulationEpidemiologyEndocrinologyBioinformaticsIntensive care medicineInternal medicinePhysiologyBiologyEnvironmental health

Abstract

fetched live from OpenAlex

Diabetes mellitus was recognized in antiquity but although there have been major advances in the understanding of diabetes and metabolism since the discovery of insulin, there was no clear or widely accepted definition of the diabetic state until the early 1980s. The World Health Organization Expert Committee defined the diabetic state as one of chronic hyperglycemia which may result from many environmental and genetic factors, often acting jointly. Hyperglycemia is due to defects in insulin secretion, insulin action or both. The major effects include long-term damage, dysfunction and failure of various organs, including the kidney, retina and cardiovascular system. The clinical symptoms vary in their intensity so the best parameter for epidemiological studies is high blood glucose. In different populations the distribution of blood glucose may vary greatly and it also increases with age. Therefore the study of the distribution of blood glucose in a population is a prerequisite to any study of diabetes in that population.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.004
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0040.003
Science and technology studies0.0010.003
Scholarly communication0.0010.002
Open science0.0010.002
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.283
Teacher spread0.257 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2001
Admission routes1
Has abstractyes

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