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Record W4205439494 · doi:10.17615/vgmv-q678

Menarche, menopause, and breast cancer risk: individual participant meta-analysis, including 118 964 women with breast cancer from 117 epidemiological studies

2021· article· en· W4205439494 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

fundA Canadian funder is recorded on the work.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueUNC Libraries · 2021
Typearticle
Languageen
FieldMedicine
TopicCancer Risks and Factors
Canadian institutionsnot available
FundersNational Institute of Child Health and Human DevelopmentNational Cancer InstituteNorwegian Institute of Public HealthUniversity of California, San FranciscoUniversity of North Carolina at Chapel HillInstituto Nacional De Salud PúblicaInstitut Gustave-RoussyWuhan UniversitySyddansk UniversitetUniversidad de Costa RicaUniversitetet i BergenOdense UniversitetshospitalMemorial Sloan-Kettering Cancer CenterUniversità degli Studi di PadovaUniversiteit MaastrichtImperial College LondonWorld Health OrganizationUniversity of Southern CaliforniaUniversity College LondonCancer Research UKLondon School of Hygiene and Tropical MedicineLoma Linda UniversityUniversity of OtagoShanghai Institute Of Planned Parenthood ResearchDeutsches KrebsforschungszentrumUniversity of PittsburghNational and Kapodistrian University of AthensKarolinska InstitutetUniversidad de ChileInstitut National de la Santé et de la Recherche MédicaleUniversity of MinnesotaUniversità degli Studi di MilanoUniversity of PennsylvaniaVanderbilt UniversityUniversity of TorontoNational University of SingaporeKaiser Permanente
KeywordsMenarcheBreast cancerEpidemiologyMenopauseMedicineCancerOncologyGynecologyObstetricsInternal medicine

Abstract

fetched live from OpenAlex

Menarche and menopause mark the onset and cessation, respectively, of ovarian activity associated with reproduction, and affect breast cancer risk. Our aim was to assess the strengths of their effects and determine whether they depend on characteristics of the tumours or the affected women.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.092
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.235
GPT teacher head0.376
Teacher spread0.141 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it