MétaCan
Menu
Back to cohort
Record W4205439494 · doi:10.17615/vgmv-q678

Menarche, menopause, and breast cancer risk: individual participant meta-analysis, including 118 964 women with breast cancer from 117 epidemiological studies

2021· article· en· W4205439494 on OpenAlexfundno aff

Bibliographic record

VenueUNC Libraries · 2021
Typearticle
Languageen
FieldMedicine
TopicCancer Risks and Factors
Canadian institutionsnot available
FundersNational Institute of Child Health and Human DevelopmentNational Cancer InstituteNorwegian Institute of Public HealthUniversity of California, San FranciscoUniversity of North Carolina at Chapel HillInstituto Nacional De Salud PúblicaInstitut Gustave-RoussyWuhan UniversitySyddansk UniversitetUniversidad de Costa RicaUniversitetet i BergenOdense UniversitetshospitalMemorial Sloan-Kettering Cancer CenterUniversità degli Studi di PadovaUniversiteit MaastrichtImperial College LondonWorld Health OrganizationUniversity of Southern CaliforniaUniversity College LondonCancer Research UKLondon School of Hygiene and Tropical MedicineLoma Linda UniversityUniversity of OtagoShanghai Institute Of Planned Parenthood ResearchDeutsches KrebsforschungszentrumUniversity of PittsburghNational and Kapodistrian University of AthensKarolinska InstitutetUniversidad de ChileInstitut National de la Santé et de la Recherche MédicaleUniversity of MinnesotaUniversità degli Studi di MilanoUniversity of PennsylvaniaVanderbilt UniversityUniversity of TorontoNational University of SingaporeKaiser Permanente
KeywordsMenarcheBreast cancerEpidemiologyMenopauseMedicineCancerOncologyGynecologyObstetricsInternal medicine

Abstract

fetched live from OpenAlex

Menarche and menopause mark the onset and cessation, respectively, of ovarian activity associated with reproduction, and affect breast cancer risk. Our aim was to assess the strengths of their effects and determine whether they depend on characteristics of the tumours or the affected women.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.007
metaresearch head score (Gemma)0.015
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: Meta-analysis
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.008
Threshold uncertainty score0.039

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0070.015
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0050.023
Bibliometrics0.0010.003
Science and technology studies0.0010.000
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.235
GPT teacher head0.376
Teacher spread0.141 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations25
Published2021
Admission routes1
Has abstractyes

Explore more

Same venueUNC LibrariesSame topicCancer Risks and FactorsFrench-language works237,207